Dennis ML - Search Results

1

New Lanthanide Tag for the Generation of Pseudocontact Shifts in DNA by Site-Specific Ligation to a Phosphorothioate Group.

Wu Z, Lee MD, Carruthers TJ, Szabo M, Dennis ML, Swarbrick JD, Graham B, Otting G. Wu Z, et al. Among authors: dennis ml. Bioconjug Chem. 2017 Jun 21;28(6):1741-1748. doi: 10.1021/acs.bioconjchem.7b00202. Epub 2017 May 15. Bioconjug Chem. 2017. PMID: 28485576

2

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

Dennis ML, Chhabra S, Wang ZC, Debono A, Dolezal O, Newman J, Pitcher NP, Rahmani R, Cleary B, Barlow N, Hattarki M, Graham B, Peat TS, Baell JB, Swarbrick JD. Dennis ML, et al. J Med Chem. 2014 Nov 26;57(22):9612-26. doi: 10.1021/jm501417f. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25357262

3

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

Swarbrick JD, Ung P, Dennis ML, Lee MD, Chhabra S, Graham B. Swarbrick JD, et al. Among authors: dennis ml. Chemistry. 2016 Jan 22;22(4):1228-32. doi: 10.1002/chem.201503139. Epub 2015 Dec 17. Chemistry. 2016. PMID: 26634335

4

Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli.

Dennis ML, Pitcher NP, Lee MD, DeBono AJ, Wang ZC, Harjani JR, Rahmani R, Cleary B, Peat TS, Baell JB, Swarbrick JD. Dennis ML, et al. J Med Chem. 2016 Jun 9;59(11):5248-63. doi: 10.1021/acs.jmedchem.6b00002. Epub 2016 Apr 26. J Med Chem. 2016. PMID: 27094768

5

Enantiomeric two-armed lanthanide-binding tags for complementary effects in paramagnetic NMR spectroscopy.

Lee MD, Dennis ML, Swarbrick JD, Graham B. Lee MD, et al. Among authors: dennis ml. Chem Commun (Camb). 2016 Jun 28;52(51):7954-7. doi: 10.1039/c6cc02325h. Epub 2016 Jun 2. Chem Commun (Camb). 2016. PMID: 27250640

6

Short two-armed lanthanide-binding tags for paramagnetic NMR spectroscopy based on chiral 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane scaffolds.

Lee MD, Dennis ML, Graham B, Swarbrick JD. Lee MD, et al. Among authors: dennis ml. Chem Commun (Camb). 2017 Dec 12;53(99):13205-13208. doi: 10.1039/c7cc07961c. Chem Commun (Camb). 2017. PMID: 29165449

7

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.

Dennis ML, Lee MD, Harjani JR, Ahmed M, DeBono AJ, Pitcher NP, Wang ZC, Chhabra S, Barlow N, Rahmani R, Cleary B, Dolezal O, Hattarki M, Aurelio L, Shonberg J, Graham B, Peat TS, Baell JB, Swarbrick JD. Dennis ML, et al. Chemistry. 2018 Feb 6;24(8):1922-1930. doi: 10.1002/chem.201704730. Epub 2018 Jan 9. Chemistry. 2018. PMID: 29171692

8

Compact, hydrophilic, lanthanide-binding tags for paramagnetic NMR spectroscopy.

Lee MD, Loh CT, Shin J, Chhabra S, Dennis ML, Otting G, Swarbrick JD, Graham B. Lee MD, et al. Among authors: dennis ml. Chem Sci. 2015 Apr 1;6(4):2614-2624. doi: 10.1039/c4sc03892d. Epub 2015 Feb 25. Chem Sci. 2015. PMID: 29560247 Free PMC article.

9

The evolving story of AtzT, a periplasmic binding protein.

Dennis ML, Esquirol L, Nebl T, Newman J, Scott C, Peat TS. Dennis ML, et al. Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):995-1002. doi: 10.1107/S2059798319013883. Epub 2019 Oct 31. Acta Crystallogr D Struct Biol. 2019. PMID: 31692473 Free PMC article.

10

The Acid/Base Profile of the Human Metabolome and Natural Products.

Manallack DT, Dennis ML, Kelly MR, Prankerd RJ, Yuriev E, Chalmers DK. Manallack DT, et al. Among authors: dennis ml. Mol Inform. 2013 Jun;32(5-6):505-15. doi: 10.1002/minf.201200167. Epub 2013 May 15. Mol Inform. 2013. PMID: 27481668

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