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Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.
Kawamata H, Peixoto P, Konrad C, Palomo G, Bredvik K, Gerges M, Valsecchi F, Petrucelli L, Ravits JM, Starkov A, Manfredi G. Kawamata H, et al. Among authors: valsecchi f. Mol Neurodegener. 2017 May 8;12(1):37. doi: 10.1186/s13024-017-0180-1. Mol Neurodegener. 2017. PMID: 28482850 Free PMC article.
cAMP and mitochondria.
Valsecchi F, Ramos-Espiritu LS, Buck J, Levin LR, Manfredi G. Valsecchi F, et al. Physiology (Bethesda). 2013 May;28(3):199-209. doi: 10.1152/physiol.00004.2013. Physiology (Bethesda). 2013. PMID: 23636265 Free PMC article. Review.
Role of soluble adenylyl cyclase in mitochondria.
Valsecchi F, Konrad C, Manfredi G. Valsecchi F, et al. Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2555-60. doi: 10.1016/j.bbadis.2014.05.035. Epub 2014 Jun 5. Biochim Biophys Acta. 2014. PMID: 24907564 Free PMC article. Review.
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, Calder EL, Carelli V, Denton TT, Beal MF, Gross SS, Manfredi G, D'Aurelio M. Chen Q, et al. Among authors: valsecchi f. Cell Metab. 2018 May 1;27(5):1007-1025.e5. doi: 10.1016/j.cmet.2018.03.002. Epub 2018 Apr 12. Cell Metab. 2018. PMID: 29657030 Free PMC article.
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C, Zippin JH, van den Heuvel J, Glickman JF, Steegborn C, Levin LR, Buck J. Ramos-Espiritu L, et al. Among authors: valsecchi f. Nat Chem Biol. 2016 Oct;12(10):838-44. doi: 10.1038/nchembio.2151. Epub 2016 Aug 22. Nat Chem Biol. 2016. PMID: 27547922 Free PMC article.
Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.
Distelmaier F, Valsecchi F, Liemburg-Apers DC, Lebiedzinska M, Rodenburg RJ, Heil S, Keijer J, Fransen J, Imamura H, Danhauser K, Seibt A, Viollet B, Gellerich FN, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ. Distelmaier F, et al. Among authors: valsecchi f. Biochim Biophys Acta. 2015 Mar;1852(3):529-40. doi: 10.1016/j.bbadis.2014.12.012. Epub 2014 Dec 20. Biochim Biophys Acta. 2015. PMID: 25536029 Free article.
48 results