Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
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Sci Transl Med. 2021 Apr 21;13(590):eabb0602. doi: 10.1126/scitranslmed.abb0602.
Sci Transl Med. 2021.
PMID: 33883272
Clinical Trial.