Sixma TK - Search Results

1

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.

Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, Ten Dijke P. Zhou F, et al. Among authors: sixma tk. EMBO J. 2017 Jun 1;36(11):1623-1639. doi: 10.15252/embj.201695372. Epub 2017 May 3. EMBO J. 2017. PMID: 28468752 Free PMC article.

2

MutL Activates UvrD by Interaction Between the MutL C-terminal Domain and the UvrD 2B Domain.

Storozhuk O, Bruekner SR, Paul A, Lebbink JHG, Sixma TK, Friedhoff P. Storozhuk O, et al. Among authors: sixma tk. J Mol Biol. 2024 Jun 1;436(11):168589. doi: 10.1016/j.jmb.2024.168589. Epub 2024 Apr 25. J Mol Biol. 2024. PMID: 38677494 Free article.

3

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

Buchwald G, van der Stoop P, Weichenrieder O, Perrakis A, van Lohuizen M, Sixma TK. Buchwald G, et al. Among authors: sixma tk. EMBO J. 2006 Jun 7;25(11):2465-74. doi: 10.1038/sj.emboj.7601144. Epub 2006 May 18. EMBO J. 2006. PMID: 16710298 Free PMC article.

4

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.

Knipscheer P, van Dijk WJ, Olsen JV, Mann M, Sixma TK. Knipscheer P, et al. Among authors: sixma tk. EMBO J. 2007 Jun 6;26(11):2797-807. doi: 10.1038/sj.emboj.7601711. Epub 2007 May 10. EMBO J. 2007. PMID: 17491593 Free PMC article.

5

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.

Luna-Vargas MP, Faesen AC, van Dijk WJ, Rape M, Fish A, Sixma TK. Luna-Vargas MP, et al. Among authors: sixma tk. EMBO Rep. 2011 Apr;12(4):365-72. doi: 10.1038/embor.2011.33. Epub 2011 Mar 18. EMBO Rep. 2011. Retraction in: EMBO Rep. 2014 Jan;15(1):121. doi: 10.1002/embr.201470010 PMID: 21415856 Free PMC article. Retracted.

6

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.

Luna-Vargas MP, Christodoulou E, Alfieri A, van Dijk WJ, Stadnik M, Hibbert RG, Sahtoe DD, Clerici M, Marco VD, Littler D, Celie PH, Sixma TK, Perrakis A. Luna-Vargas MP, et al. Among authors: sixma tk. J Struct Biol. 2011 Aug;175(2):113-9. doi: 10.1016/j.jsb.2011.03.017. Epub 2011 Mar 29. J Struct Biol. 2011. PMID: 21453775

7

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: sixma tk. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

8

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

Smit JJ, Monteferrario D, Noordermeer SM, van Dijk WJ, van der Reijden BA, Sixma TK. Smit JJ, et al. Among authors: sixma tk. EMBO J. 2012 Oct 3;31(19):3833-44. doi: 10.1038/emboj.2012.217. Epub 2012 Aug 3. EMBO J. 2012. PMID: 22863777 Free PMC article.

9

RBR E3-ligases at work.

Smit JJ, Sixma TK. Smit JJ, et al. Among authors: sixma tk. EMBO Rep. 2014 Feb;15(2):142-54. doi: 10.1002/embr.201338166. Epub 2014 Jan 27. EMBO Rep. 2014. PMID: 24469331 Free PMC article. Review.

10

The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchange.

Clerici M, Luna-Vargas MP, Faesen AC, Sixma TK. Clerici M, et al. Among authors: sixma tk. Nat Commun. 2014 Nov 18;5:5399. doi: 10.1038/ncomms6399. Nat Commun. 2014. PMID: 25404403 Free PMC article.

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