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2-thioxanthines are mechanism-based inactivators of myeloperoxidase that block oxidative stress during inflammation.
Tidén AK, Sjögren T, Svensson M, Bernlind A, Senthilmohan R, Auchère F, Norman H, Markgren PO, Gustavsson S, Schmidt S, Lundquist S, Forbes LV, Magon NJ, Paton LN, Jameson GN, Eriksson H, Kettle AJ. Tidén AK, et al. Among authors: eriksson h. J Biol Chem. 2011 Oct 28;286(43):37578-89. doi: 10.1074/jbc.M111.266981. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880720 Free PMC article.
First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.
Borgegard T, Juréus A, Olsson F, Rosqvist S, Sabirsh A, Rotticci D, Paulsen K, Klintenberg R, Yan H, Waldman M, Stromberg K, Nord J, Johansson J, Regner A, Parpal S, Malinowsky D, Radesater AC, Li T, Singh R, Eriksson H, Lundkvist J. Borgegard T, et al. Among authors: eriksson h. J Biol Chem. 2012 Apr 6;287(15):11810-9. doi: 10.1074/jbc.M111.305227. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334705 Free PMC article.
Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates.
Forbes LV, Sjögren T, Auchère F, Jenkins DW, Thong B, Laughton D, Hemsley P, Pairaudeau G, Turner R, Eriksson H, Unitt JF, Kettle AJ. Forbes LV, et al. Among authors: eriksson h. J Biol Chem. 2013 Dec 20;288(51):36636-47. doi: 10.1074/jbc.M113.507756. Epub 2013 Nov 5. J Biol Chem. 2013. PMID: 24194519 Free PMC article.
Al adjuvants can be tracked in viable cells by lumogallion staining.
Mile I, Svensson A, Darabi A, Mold M, Siesjö P, Eriksson H. Mile I, et al. Among authors: eriksson h. J Immunol Methods. 2015 Jul;422:87-94. doi: 10.1016/j.jim.2015.04.008. Epub 2015 Apr 17. J Immunol Methods. 2015. PMID: 25896212 Free article.
735 results