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Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions.
Held FE, Guryev AA, Fröhlich T, Hampel F, Kahnt A, Hutterer C, Steingruber M, Bahsi H, von Bojničić-Kninski C, Mattes DS, Foertsch TC, Nesterov-Mueller A, Marschall M, Tsogoeva SB. Held FE, et al. Among authors: frohlich t. Nat Commun. 2017 May 2;8:15071. doi: 10.1038/ncomms15071. Nat Commun. 2017. PMID: 28462939 Free PMC article.
Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.
Fröhlich T, Reiter C, Ibrahim MM, Beutel J, Hutterer C, Zeitträger I, Bahsi H, Leidenberger M, Friedrich O, Kappes B, Efferth T, Marschall M, Tsogoeva SB. Fröhlich T, et al. ACS Omega. 2017 Jun 30;2(6):2422-2431. doi: 10.1021/acsomega.7b00310. Epub 2017 Jun 1. ACS Omega. 2017. PMID: 30023664 Free PMC article.
New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids.
Reiter C, Fröhlich T, Zeino M, Marschall M, Bahsi H, Leidenberger M, Friedrich O, Kappes B, Hampel F, Efferth T, Tsogoeva SB. Reiter C, et al. Among authors: frohlich t. Eur J Med Chem. 2015 Jun 5;97:164-72. doi: 10.1016/j.ejmech.2015.04.053. Epub 2015 Apr 28. Eur J Med Chem. 2015. PMID: 25965779
Artemisinin-derived dimers from a chemical perspective.
Çapcı A, Herrmann L, Sampath Kumar HM, Fröhlich T, Tsogoeva SB. Çapcı A, et al. Among authors: frohlich t. Med Res Rev. 2021 Nov;41(6):2927-2970. doi: 10.1002/med.21814. Epub 2021 Jun 11. Med Res Rev. 2021. PMID: 34114227 Review.
241 results