Orchard PJ - Search Results

1

Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I.

Belur LR, Temme A, Podetz-Pedersen KM, Riedl M, Vulchanova L, Robinson N, Hanson LR, Kozarsky KF, Orchard PJ, Frey WH 2nd, Low WC, McIvor RS. Belur LR, et al. Among authors: orchard pj. Hum Gene Ther. 2017 Jul;28(7):576-587. doi: 10.1089/hum.2017.187. Epub 2017 Apr 20. Hum Gene Ther. 2017. PMID: 28462595 Free PMC article.

2

GM-CSF-induced internal autocrine proliferation occurs in a compartment outside of the endoplasmic reticulum.

Orchard PJ, McIvor RS, Singh HA, Blazar BR. Orchard PJ, et al. Exp Hematol. 1995 Jul;23(7):573-82. Exp Hematol. 1995. PMID: 7601247 No abstract available.

3

Transfection of the mouse ICAM-1 gene into murine neuroblastoma enhances susceptibility to lysis, reduces in vivo tumorigenicity and decreases ICAM-2-dependent killing.

Katsanis E, Bausero MA, Xu H, Orchard PJ, Xu Z, McIvor RS, Brian AA, Blazar BR. Katsanis E, et al. Among authors: orchard pj. Cancer Immunol Immunother. 1994 Feb;38(2):135-41. doi: 10.1007/BF01526209. Cancer Immunol Immunother. 1994. PMID: 7905790 Free PMC article.

4

Interleukin-2 gene transfer into murine neuroblastoma decreases tumorigenicity and enhances systemic immunity causing regression of preestablished retroperitoneal tumors.

Katsanis E, Orchard PJ, Bausero MA, Gorden KB, McIvor RS, Blazar BR. Katsanis E, et al. Among authors: orchard pj. J Immunother Emphasis Tumor Immunol. 1994 Feb;15(2):81-90. doi: 10.1097/00002371-199402000-00001. J Immunother Emphasis Tumor Immunol. 1994. PMID: 8136949

5

Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.

Orchard PJ, Detrick RA, Gorden K, Dunbar CE, Vallera DA, Taylor P, McIvor RS, Blazar BR. Orchard PJ, et al. Exp Hematol. 1993 Aug;21(9):1245-54. Exp Hematol. 1993. PMID: 8330649

6

Interleukin-2 secretion by transduced and unselected BDL-2 lymphoma results in increased survival in mice with previously established disseminated disease.

Orchard PJ, Katsanis E, Boyer M, May C, McIvor RS, Blazar BR. Orchard PJ, et al. Cancer Biother Radiopharm. 1996 Apr;11(2):155-64. doi: 10.1089/cbr.1996.11.155. Cancer Biother Radiopharm. 1996. PMID: 10851532

7

Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor.

Orchard PJ, Blazar BR, Burger S, Levine B, Basso L, Nelson DM, Gordon K, McIvor RS, Wagner JE, Miller JS. Orchard PJ, et al. Hum Gene Ther. 2002 May 20;13(8):979-88. doi: 10.1089/10430340252939087. Hum Gene Ther. 2002. PMID: 12031130

8

Human nerve growth factor receptor and cytosine deaminase fusion genes.

Lewis VA, Basso L, Blake N, Salo J, Lund TC, McIvor RS, Orchard PJ. Lewis VA, et al. Among authors: orchard pj. Hum Gene Ther. 2003 Jul 1;14(10):1009-16. doi: 10.1089/104303403766682269. Hum Gene Ther. 2003. PMID: 12869218

9

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system.

Huang X, Wilber AC, Bao L, Tuong D, Tolar J, Orchard PJ, Levine BL, June CH, McIvor RS, Blazar BR, Zhou X. Huang X, et al. Among authors: orchard pj. Blood. 2006 Jan 15;107(2):483-91. doi: 10.1182/blood-2005-05-2133. Epub 2005 Sep 27. Blood. 2006. PMID: 16189271 Free PMC article.

10

Coexpression of the uracil phosphoribosyltransferase gene with a chimeric human nerve growth factor receptor/cytosine deaminase fusion gene, using a single retroviral vector, augments cytotoxicity of transduced human T cells exposed to 5-fluorocytosine.

O'Brien TA, Tuong DT, Basso LM, McIvor RS, Orchard PJ. O'Brien TA, et al. Among authors: orchard pj. Hum Gene Ther. 2006 May;17(5):518-30. doi: 10.1089/hum.2006.17.518. Hum Gene Ther. 2006. PMID: 16716109

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