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Page 1
Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP. Cameron P, et al. Among authors: settle ah. Nat Methods. 2017 Jun;14(6):600-606. doi: 10.1038/nmeth.4284. Epub 2017 May 1. Nat Methods. 2017. PMID: 28459459
NmeCas9 is an intrinsically high-fidelity genome-editing platform.
Amrani N, Gao XD, Liu P, Edraki A, Mir A, Ibraheim R, Gupta A, Sasaki KE, Wu T, Donohoue PD, Settle AH, Lied AM, McGovern K, Fuller CK, Cameron P, Fazzio TG, Zhu LJ, Wolfe SA, Sontheimer EJ. Amrani N, et al. Among authors: settle ah. Genome Biol. 2018 Dec 5;19(1):214. doi: 10.1186/s13059-018-1591-1. Genome Biol. 2018. PMID: 30518407 Free PMC article.
A perception-based nanosensor platform to detect cancer biomarkers.
Yaari Z, Yang Y, Apfelbaum E, Cupo C, Settle AH, Cullen Q, Cai W, Long Roche K, Levine DA, Fleisher M, Ramanathan L, Zheng M, Jagota A, Heller DA. Yaari Z, et al. Among authors: settle ah. Sci Adv. 2021 Nov 19;7(47):eabj0852. doi: 10.1126/sciadv.abj0852. Epub 2021 Nov 19. Sci Adv. 2021. PMID: 34797711 Free PMC article.
β2 integrins impose a mechanical checkpoint on macrophage phagocytosis.
Settle AH, Winer BY, de Jesus MM, Seeman L, Wang Z, Chan E, Romin Y, Li Z, Miele MM, Hendrickson RC, Vorselen D, Perry JSA, Huse M. Settle AH, et al. Nat Commun. 2024 Sep 18;15(1):8182. doi: 10.1038/s41467-024-52453-9. Nat Commun. 2024. PMID: 39294148 Free PMC article.
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity.
de Jesus M, Settle AH, Vorselen D, Gaetjens TK, Galiano M, Romin Y, Lee E, Wong YY, Fu TM, Santosa E, Winer BY, Tamzalit F, Wang MS, Santella A, Bao Z, Sun JC, Shah P, Theriot JA, Abel SM, Huse M. de Jesus M, et al. Among authors: settle ah. Sci Immunol. 2024 Jun 28;9(96):eadj2898. doi: 10.1126/sciimmunol.adj2898. Epub 2024 Jun 28. Sci Immunol. 2024. PMID: 38941478
Plasma membrane abundance dictates phagocytic capacity and functional cross-talk in myeloid cells.
Winer BY, Settle AH, Yakimov AM, Jeronimo C, Lazarov T, Tipping M, Saoi M, Sawh A, Sepp AL, Galiano M, Perry JSA, Wong YY, Geissmann F, Cross J, Zhou T, Kam LC, Pasolli HA, Hohl T, Cyster JG, Weiner OD, Huse M. Winer BY, et al. Among authors: settle ah. Sci Immunol. 2024 Jun 7;9(96):eadl2388. doi: 10.1126/sciimmunol.adl2388. Epub 2024 Jun 7. Sci Immunol. 2024. PMID: 38848343 Free PMC article.
Author Correction: Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP. Cameron P, et al. Among authors: settle ah. Nat Methods. 2023 Dec;20(12):2068. doi: 10.1038/s41592-023-02114-4. Nat Methods. 2023. PMID: 37945910 No abstract available.
Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells.
Winer BY, Settle AH, Yakimov AM, Jeronimo C, Lazarov T, Tipping M, Saoi M, Sawh A, Sepp AL, Galiano M, Wong YY, Perry JSA, Geissmann F, Cross J, Zhou T, Kam LC, Pasoli HA, Hohl T, Cyster JG, Weiner OD, Huse M. Winer BY, et al. Among authors: settle ah. bioRxiv [Preprint]. 2023 Sep 13:2023.09.12.556572. doi: 10.1101/2023.09.12.556572. bioRxiv. 2023. Update in: Sci Immunol. 2024 Jun 7;9(96):eadl2388. doi: 10.1126/sciimmunol.adl2388 PMID: 37745515 Free PMC article. Updated. Preprint.
11 results