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The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: jaarsma d. Front Aging. 2022 Oct 12;3:1005322. doi: 10.3389/fragi.2022.1005322. eCollection 2022. Front Aging. 2022. PMID: 36313181 Free PMC article.
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway.
Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. Kushner SA, et al. Among authors: jaarsma d. J Neurosci. 2005 Oct 19;25(42):9721-34. doi: 10.1523/JNEUROSCI.2836-05.2005. J Neurosci. 2005. PMID: 16237176 Free PMC article.
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
de Waard MC, van der Pluijm I, Zuiderveen Borgesius N, Comley LH, Haasdijk ED, Rijksen Y, Ridwan Y, Zondag G, Hoeijmakers JH, Elgersma Y, Gillingwater TH, Jaarsma D. de Waard MC, et al. Among authors: jaarsma d. Acta Neuropathol. 2010 Oct;120(4):461-75. doi: 10.1007/s00401-010-0715-9. Epub 2010 Jul 4. Acta Neuropathol. 2010. PMID: 20602234 Free PMC article.
Cockayne syndrome pathogenesis: lessons from mouse models.
Jaarsma D, van der Pluijm I, van der Horst GT, Hoeijmakers JH. Jaarsma D, et al. Mech Ageing Dev. 2013 May-Jun;134(5-6):180-95. doi: 10.1016/j.mad.2013.04.003. Epub 2013 Apr 13. Mech Ageing Dev. 2013. PMID: 23591128 Review.
Arc expression identifies the lateral amygdala fear memory trace.
Gouty-Colomer LA, Hosseini B, Marcelo IM, Schreiber J, Slump DE, Yamaguchi S, Houweling AR, Jaarsma D, Elgersma Y, Kushner SA. Gouty-Colomer LA, et al. Among authors: jaarsma d. Mol Psychiatry. 2016 Mar;21(3):364-75. doi: 10.1038/mp.2015.18. Epub 2015 Mar 24. Mol Psychiatry. 2016. PMID: 25802982 Free PMC article.
Arc expression identifies the lateral amygdala fear memory trace.
Gouty-Colomer LA, Hosseini B, Marcelo IM, Schreiber J, Slump DE, Yamaguchi S, Houweling AR, Jaarsma D, Elgersma Y, Kushner SA. Gouty-Colomer LA, et al. Among authors: jaarsma d. Mol Psychiatry. 2016 Aug;21(8):1153. doi: 10.1038/mp.2016.91. Epub 2016 May 24. Mol Psychiatry. 2016. PMID: 27217149 Free PMC article. No abstract available.
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice.
Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET. Birkisdóttir MB, et al. Among authors: jaarsma d. Aging Cell. 2021 Feb;20(2):e13302. doi: 10.1111/acel.13302. Epub 2021 Jan 23. Aging Cell. 2021. PMID: 33484480 Free PMC article.
149 results