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Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.
Benavides-Serrato A, Lee J, Holmes B, Landon KA, Bashir T, Jung ME, Lichtenstein A, Gera J. Benavides-Serrato A, et al. Among authors: jung me. PLoS One. 2017 Apr 28;12(4):e0176599. doi: 10.1371/journal.pone.0176599. eCollection 2017. PLoS One. 2017. Retraction in: PLoS One. 2023 Sep 8;18(9):e0291490. doi: 10.1371/journal.pone.0291490 PMID: 28453552 Free PMC article. Retracted.
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion.
Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B. Vigant F, et al. Among authors: jung me. PLoS Pathog. 2013;9(4):e1003297. doi: 10.1371/journal.ppat.1003297. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637597 Free PMC article.
Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.
Holmes B, Lee J, Landon KA, Benavides-Serrato A, Bashir T, Jung ME, Lichtenstein A, Gera J. Holmes B, et al. Among authors: jung me. J Biol Chem. 2016 Jul 1;291(27):14146-14159. doi: 10.1074/jbc.M116.726927. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226604 Free PMC article.
Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.
Shi Y, Daniels-Wells TR, Frost P, Lee J, Finn RS, Bardeleben C, Penichet ML, Jung ME, Gera J, Lichtenstein A. Shi Y, et al. Among authors: jung me. Cancer Res. 2016 Oct 1;76(19):5822-5831. doi: 10.1158/0008-5472.CAN-16-1019. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530328 Free PMC article.
337 results