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Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.
Coffey SR, Bragg RM, Minnig S, Ament SA, Cantle JP, Glickenhaus A, Shelnut D, Carrillo JM, Shuttleworth DD, Rodier JA, Noguchi K, Bennett CF, Price ND, Kordasiewicz HB, Carroll JB. Coffey SR, et al. Among authors: glickenhaus a. PLoS One. 2017 Apr 28;12(4):e0175968. doi: 10.1371/journal.pone.0175968. eCollection 2017. PLoS One. 2017. PMID: 28453524 Free PMC article.
Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.
Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB. Bragg RM, et al. Among authors: glickenhaus a. Sci Rep. 2017 Feb 8;7:41570. doi: 10.1038/srep41570. Sci Rep. 2017. PMID: 28176805 Free PMC article.
Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.
Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB. Bragg RM, et al. Among authors: glickenhaus a. Sci Rep. 2017 Mar 28;7:44960. doi: 10.1038/srep44960. Sci Rep. 2017. PMID: 28350386 Free PMC article. No abstract available.