Zhu S - Search Results

1

Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics.

Lento C, Zhu S, Brown KA, Knox R, Liuni P, Wilson DJ. Lento C, et al. Among authors: zhu s. J Vis Exp. 2017 Apr 17;(122):55464. doi: 10.3791/55464. J Vis Exp. 2017. PMID: 28448048 Free PMC article.

2

Measuring dynamics in weakly structured regions of proteins using microfluidics-enabled subsecond H/D exchange mass spectrometry.

Rob T, Liuni P, Gill PK, Zhu S, Balachandran N, Berti PJ, Wilson DJ. Rob T, et al. Among authors: zhu s. Anal Chem. 2012 Apr 17;84(8):3771-9. doi: 10.1021/ac300365u. Epub 2012 Apr 6. Anal Chem. 2012. PMID: 22458633

3

Oxidative protein labeling with analysis by mass spectrometry for the study of structure, folding, and dynamics.

Liuni P, Zhu S, Wilson DJ. Liuni P, et al. Among authors: zhu s. Antioxid Redox Signal. 2014 Jul 20;21(3):497-510. doi: 10.1089/ars.2014.5850. Epub 2014 Mar 6. Antioxid Redox Signal. 2014. PMID: 24512178 Review.

4

Differential Mobility Spectrometry-Hydrogen Deuterium Exchange (DMS-HDX) as a Probe of Protein Conformation in Solution.

Zhu S, Campbell JL, Chernushevich I, Le Blanc JC, Wilson DJ. Zhu S, et al. J Am Soc Mass Spectrom. 2016 Jun;27(6):991-9. doi: 10.1007/s13361-016-1364-6. Epub 2016 Mar 10. J Am Soc Mass Spectrom. 2016. PMID: 26965162

5

Enhanced Binding Affinity via Destabilization of the Unbound State: A Millisecond Hydrogen-Deuterium Exchange Study of the Interaction between p53 and a Pleckstrin Homology Domain.

Zhu S, Khatun R, Lento C, Sheng Y, Wilson DJ. Zhu S, et al. Biochemistry. 2017 Aug 15;56(32):4127-4133. doi: 10.1021/acs.biochem.7b00193. Epub 2017 Jul 19. Biochemistry. 2017. PMID: 28696098

6

Suppressing allostery in epitope mapping experiments using millisecond hydrogen / deuterium exchange mass spectrometry.

Deng B, Zhu S, Macklin AM, Xu J, Lento C, Sljoka A, Wilson DJ. Deng B, et al. Among authors: zhu s. MAbs. 2017 Nov/Dec;9(8):1327-1336. doi: 10.1080/19420862.2017.1379641. Epub 2017 Sep 21. MAbs. 2017. PMID: 28933661 Free PMC article.

7

Epitope screening using Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS): An accelerated workflow for evaluation of lead monoclonal antibodies.

Zhu S, Liuni P, Chen T, Houy C, Wilson DJ, James DA. Zhu S, et al. Biotechnol J. 2022 Feb;17(2):e2100358. doi: 10.1002/biot.202100358. Epub 2021 Nov 21. Biotechnol J. 2022. PMID: 34747565

8

Hyperphosphorylation of intrinsically disordered tau protein induces an amyloidogenic shift in its conformational ensemble.

Zhu S, Shala A, Bezginov A, Sljoka A, Audette G, Wilson DJ. Zhu S, et al. PLoS One. 2015 Mar 13;10(3):e0120416. doi: 10.1371/journal.pone.0120416. eCollection 2015. PLoS One. 2015. PMID: 25767879 Free PMC article.

9

Conformational Dynamics and Allostery in Pyruvate Kinase.

Donovan KA, Zhu S, Liuni P, Peng F, Kessans SA, Wilson DJ, Dobson RC. Donovan KA, et al. Among authors: zhu s. J Biol Chem. 2016 Apr 22;291(17):9244-56. doi: 10.1074/jbc.M115.676270. Epub 2016 Feb 15. J Biol Chem. 2016. PMID: 26879751 Free PMC article.

10

Hydrogen-Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin.

Zhu S, Liuni P, Ettorre L, Chen T, Szeto J, Carpick B, James DA, Wilson DJ. Zhu S, et al. Biochemistry. 2019 Feb 12;58(6):646-656. doi: 10.1021/acs.biochem.8b01123. Epub 2019 Jan 3. Biochemistry. 2019. PMID: 30560647

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