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Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ.
Allen RA, Brookings DC, Powell MJ, Delgado J, Shuttleworth LK, Merriman M, Fahy IJ, Tewari R, Silva JP, Healy LJ, Davies GCG, Twomey B, Cutler RM, Kotian A, Crosby A, McCluskey G, Watt GF, Payne A. Allen RA, et al. Among authors: watt gf. J Pharmacol Exp Ther. 2017 Jun;361(3):429-440. doi: 10.1124/jpet.116.237347. Epub 2017 Apr 25. J Pharmacol Exp Ther. 2017. PMID: 28442583
Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion.
McDonald IM, Black JW, Buck IM, Dunstone DJ, Griffin EP, Harper EA, Hull RA, Kalindjian SB, Lilley EJ, Linney ID, Pether MJ, Roberts SP, Shaxted ME, Spencer J, Steel KI, Sykes DA, Walker MK, Watt GF, Wright L, Wright PT, Xun W. McDonald IM, et al. Among authors: watt gf. J Med Chem. 2007 Jun 28;50(13):3101-12. doi: 10.1021/jm070139l. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536796
Definition and localization of histamine H2 receptors.
Shankley NP, Watt GF, Black JW. Shankley NP, et al. Among authors: watt gf. Eur J Clin Invest. 1995 Mar;25 Suppl 1:12-8. Eur J Clin Invest. 1995. PMID: 7781671 Review. No abstract available.
Optimization of the in vitro and in vivo properties of a novel series of 2,4,5-trisubstituted imidazoles as potent cholecystokinin-2 (CCK2) antagonists.
Buck IM, Black JW, Cooke T, Dunstone DJ, Gaffen JD, Griffin EP, Harper EA, Hull RA, Kalindjian SB, Lilley EJ, Linney ID, Low CM, McDonald IM, Pether MJ, Roberts SP, Shankley NP, Shaxted ME, Steel KI, Sykes DA, Tozer MJ, Watt GF, Walker MK, Wright L, Wright PT. Buck IM, et al. Among authors: watt gf. J Med Chem. 2005 Nov 3;48(22):6803-12. doi: 10.1021/jm0490686. J Med Chem. 2005. PMID: 16250639
Nonpeptide cholecystokinin-2 receptor agonists.
Kalindjian SB, Dunstone DJ, Low CM, Pether MJ, Roberts SP, Tozer MJ, Watt GF, Shankley NP. Kalindjian SB, et al. Among authors: watt gf. J Med Chem. 2001 Apr 12;44(8):1125-33. doi: 10.1021/jm0010668. J Med Chem. 2001. PMID: 11312913
32 results