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Discovery and optimization of selective FGFR4 inhibitors via scaffold hopping.
Wang Y, Chen Z, Dai M, Sun P, Wang C, Gao Y, Zhao H, Zeng W, Shen L, Mao W, Wang T, Hu G, Li J, Chen S, Long C, Chen X, Liu J, Zhang Y. Wang Y, et al. Among authors: chen z, chen s, chen x. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2420-2423. doi: 10.1016/j.bmcl.2017.04.014. Epub 2017 Apr 5. Bioorg Med Chem Lett. 2017. PMID: 28433531
Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.
Xiao H, Li P, Li X, He H, Wang J, Guo F, Zhang J, Wei L, Zhang H, Shi Y, Hou L, Shen L, Chen Z, Du C, Fu S, Zhang P, Hao F, Wang P, Xu D, Liang W, Tian X, Zhang A, Cheng X, Yang L, Wang X, Zhang X, Li J, Chen S. Xiao H, et al. Among authors: chen z, chen s. ACS Med Chem Lett. 2017 Oct 31;8(12):1246-1251. doi: 10.1021/acsmedchemlett.7b00318. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259742 Free PMC article.
Design, synthesis and pharmacological evaluation of 4-(3-chloro-4-(3-cyclopropylthioureido)-2-fluorophenoxy)-7-methoxyquinoline-6-carboxamide (WXFL-152): a novel triple angiokinase inhibitor for cancer therapy.
Yao Y, Liu Z, Zhao M, Chen Z, Li P, Zhang Y, Wang Y, Zhao C, Long C, Chen X, Yang J. Yao Y, et al. Among authors: chen z, chen x. Acta Pharm Sin B. 2020 Aug;10(8):1453-1475. doi: 10.1016/j.apsb.2020.04.002. Epub 2020 Apr 19. Acta Pharm Sin B. 2020. PMID: 32963943 Free PMC article.
Corrigendum to "Huashi baidu granule alleviates inflammation and lung edema by suppressing the NLRP3/caspase-1/GSDMD-N pathway and promoting fluid clearance in a porcine reproductive and respiratory syndrome (PRRS) model" [J. Ethnopharmacol. 340 (2025) 119207].
Zhang FL, Chen YL, Luo ZY, Song ZB, Chen Z, Zhang JX, Zheng ZZ, Tan XM. Zhang FL, et al. Among authors: chen z. J Ethnopharmacol. 2025 Jan 3:119317. doi: 10.1016/j.jep.2024.119317. Online ahead of print. J Ethnopharmacol. 2025. PMID: 39755490 No abstract available.
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