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Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report.
Newman JH, Rich S, Abman SH, Alexander JH, Barnard J, Beck GJ, Benza RL, Bull TM, Chan SY, Chun HJ, Doogan D, Dupuis J, Erzurum SC, Frantz RP, Geraci M, Gillies H, Gladwin M, Gray MP, Hemnes AR, Herbst RS, Hernandez AF, Hill NS, Horn EM, Hunter K, Jing ZC, Johns R, Kaul S, Kawut SM, Lahm T, Leopold JA, Lewis GD, Mathai SC, McLaughlin VV, Michelakis ED, Nathan SD, Nichols W, Page G, Rabinovitch M, Rich J, Rischard F, Rounds S, Shah SJ, Tapson VF, Lowy N, Stockbridge N, Weinmann G, Xiao L. Newman JH, et al. Among authors: chan sy. Am J Respir Crit Care Med. 2017 Jun 15;195(12):1661-1670. doi: 10.1164/rccm.201701-0150WS. Am J Respir Crit Care Med. 2017. PMID: 28430547 Free PMC article.
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.
Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Maron BA, et al. Among authors: chan sy. Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722. Epub 2012 Jul 11. Circulation. 2012. PMID: 22787113 Free PMC article.
Update in Pulmonary Vascular Disease 2016 and 2017.
Brittain EL, Thennapan T, Maron BA, Chan SY, Austin ED, Spiekerkoetter E, Bogaard HJ, Guignabert C, Paulin R, Machado RF, Yu PB. Brittain EL, et al. Among authors: chan sy. Am J Respir Crit Care Med. 2018 Jul 1;198(1):13-23. doi: 10.1164/rccm.201801-0062UP. Am J Respir Crit Care Med. 2018. PMID: 29533671 Free PMC article. No abstract available.
A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
Kuebler WM, Nicolls MR, Olschewski A, Abe K, Rabinovitch M, Stewart D, Chan SY, Morrell NW, Archer SL, Spiekerkoetter E. Kuebler WM, et al. Among authors: chan sy. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L502-L516. doi: 10.1152/ajplung.00150.2018. Epub 2018 Jun 7. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29877097 Free PMC article. Review.
Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome.
Stearman RS, Bui QM, Speyer G, Handen A, Cornelius AR, Graham BB, Kim S, Mickler EA, Tuder RM, Chan SY, Geraci MW. Stearman RS, et al. Among authors: chan sy. Am J Respir Cell Mol Biol. 2019 Jun;60(6):637-649. doi: 10.1165/rcmb.2018-0368OC. Am J Respir Cell Mol Biol. 2019. PMID: 30562042 Free PMC article.
1,112 results