Mapping protein-protein proximity in the purinosome.
Deng Y, Gam J, French JB, Zhao H, An S, Benkovic SJ.
Deng Y, et al. Among authors: an s.
J Biol Chem. 2012 Oct 19;287(43):36201-7. doi: 10.1074/jbc.M112.407056. Epub 2012 Sep 6.
J Biol Chem. 2012.
PMID: 22955281
Free PMC article.
The enzymes in the human de novo purine synthesis pathway were found to form a cellular complex, the purinosome, upon culturing cells in purine-depleted medium (An, S., Kumar R., Sheets, E. D., and Benkovic, S. J. (2008) Science 320, 103-106). Purinosome form …
The enzymes in the human de novo purine synthesis pathway were found to form a cellular complex, the purinosome, upon culturing cells in pur …