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Page 1
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.
Kato I, Nishinaka Y, Nakamura M, Akarca AU, Niwa A, Ozawa H, Yoshida K, Mori M, Wang D, Morita M, Ueno H, Shiozawa Y, Shiraishi Y, Miyano S, Gupta R, Umeda K, Watanabe K, Koh K, Adachi S, Heike T, Saito MK, Sanada M, Ogawa S, Marafioti T, Watanabe A, Nakahata T, Enver T. Kato I, et al. Among authors: akarca au. Blood. 2017 Jun 8;129(23):3126-3129. doi: 10.1182/blood-2016-06-721712. Epub 2017 Apr 19. Blood. 2017. PMID: 28424164 Free PMC article. No abstract available.
ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.
Flynn MJ, Zammarchi F, Tyrer PC, Akarca AU, Janghra N, Britten CE, Havenith CE, Levy JN, Tiberghien A, Masterson LA, Barry C, D'Hooge F, Marafioti T, Parren PW, Williams DG, Howard PW, van Berkel PH, Hartley JA. Flynn MJ, et al. Among authors: akarca au. Mol Cancer Ther. 2016 Nov;15(11):2709-2721. doi: 10.1158/1535-7163.MCT-16-0233. Epub 2016 Aug 17. Mol Cancer Ther. 2016. PMID: 27535974
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress.
Burt R, Dey A, Aref S, Aguiar M, Akarca A, Bailey K, Day W, Hooper S, Kirkwood A, Kirschner K, Lee SW, Lo Celso C, Manji J, Mansour MR, Marafioti T, Mitchell RJ, Muirhead RC, Cheuk Yan Ng K, Pospori C, Puccio I, Zuborne-Alapi K, Sahai E, Fielding AK. Burt R, et al. Blood. 2019 Oct 24;134(17):1415-1429. doi: 10.1182/blood.2019001398. Blood. 2019. PMID: 31501154 Free PMC article.
Impact of MYC and BCL2 double expression on outcomes in primary CNS lymphoma: a UK multicenter analysis.
Poynton E, Chernucha E, Day J, Prodger C, Hopkins D, Rakesh P, O'Neill T, Thakrar N, Akarca A, Jamal E, Ali A, Kirkwood AA, Pomplun S, Marafioti T, Calaminici M, Greaves P, Chaganti S, McKay P, Smith J, Eyre TA, Martinez-Calle N, Cwynarski K, Fox CP, Okosun J. Poynton E, et al. Blood Adv. 2024 Apr 9;8(7):1772-1775. doi: 10.1182/bloodadvances.2023011426. Blood Adv. 2024. PMID: 38039509 Free PMC article. No abstract available.
Circulating tumour cells and their association with bone metastases in patients with neuroendocrine tumours.
Rizzo FM, Vesely C, Childs A, Marafioti T, Khan MS, Mandair D, Cives M, Ensell L, Lowe H, Akarca AU, Luong T, Caplin M, Toumpanakis C, Krell D, Thirlwell C, Silvestris F, Hartley JA, Meyer T. Rizzo FM, et al. Among authors: akarca au. Br J Cancer. 2019 Feb;120(3):294-300. doi: 10.1038/s41416-018-0367-4. Epub 2019 Jan 14. Br J Cancer. 2019. PMID: 30636773 Free PMC article.
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