Boura-Halfon S - Search Results

1

Prolonged Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Impairs β-Cell Function In Vivo.

Isaac R, Vinik Y, Boura-Halfon S, Farack L, Streim S, Elhanany E, Kam Z, Zick Y. Isaac R, et al. Diabetes. 2017 Jul;66(7):1879-1889. doi: 10.2337/db16-0827. Epub 2017 Apr 19. Diabetes. 2017. PMID: 28424159

2

The juxtamembrane but not the carboxyl-terminal domain of the insulin receptor mediates insulin's metabolic functions in primary adipocytes and cultured hepatoma cells.

Paz K, Boura-Halfon S, Wyatt LS, LeRoith D, Zick Y. Paz K, et al. J Mol Endocrinol. 2000 Jun;24(3):419-32. doi: 10.1677/jme.0.0240419. J Mol Endocrinol. 2000. PMID: 10828835

3

Extracellular matrix proteins modulate endocytosis of the insulin receptor.

Boura-Halfon S, Voliovitch H, Feinstein R, Paz K, Zick Y. Boura-Halfon S, et al. J Biol Chem. 2003 May 2;278(18):16397-404. doi: 10.1074/jbc.M212385200. Epub 2003 Feb 19. J Biol Chem. 2003. PMID: 12594209 Free article.

4

Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.

Liu YF, Herschkovitz A, Boura-Halfon S, Ronen D, Paz K, Leroith D, Zick Y. Liu YF, et al. Mol Cell Biol. 2004 Nov;24(21):9668-81. doi: 10.1128/MCB.24.21.9668-9681.2004. Mol Cell Biol. 2004. PMID: 15485932 Free PMC article.

5

Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance.

Herschkovitz A, Liu YF, Ilan E, Ronen D, Boura-Halfon S, Zick Y. Herschkovitz A, et al. J Biol Chem. 2007 Jun 22;282(25):18018-18027. doi: 10.1074/jbc.M610949200. Epub 2007 Apr 19. J Biol Chem. 2007. Retraction in: J Biol Chem. 2018 May 11;293(19):7266. doi: 10.1074/jbc.W118.003468 PMID: 17446166 Free article. Retracted.

6

Phosphorylation of IRS proteins, insulin action, and insulin resistance.

Boura-Halfon S, Zick Y. Boura-Halfon S, et al. Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E581-91. doi: 10.1152/ajpendo.90437.2008. Epub 2008 Aug 26. Am J Physiol Endocrinol Metab. 2009. PMID: 18728222 Free article. Review.

7

Serine kinases of insulin receptor substrate proteins.

Boura-Halfon S, Zick Y. Boura-Halfon S, et al. Vitam Horm. 2009;80:313-49. doi: 10.1016/S0083-6729(08)00612-2. Vitam Horm. 2009. PMID: 19251043 Review.

8

Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress.

Gurevitch D, Boura-Halfon S, Isaac R, Shahaf G, Alberstein M, Ronen D, Lewis EC, Zick Y. Gurevitch D, et al. Diabetes. 2010 Sep;59(9):2188-97. doi: 10.2337/db09-0890. Epub 2010 Jun 14. Diabetes. 2010. PMID: 20547979 Free PMC article.

9

A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1).

Boura-Halfon S, Shuster-Meiseles T, Beck A, Petrovich K, Gurevitch D, Ronen D, Zick Y. Boura-Halfon S, et al. Mol Endocrinol. 2010 Nov;24(11):2179-92. doi: 10.1210/me.2010-0072. Epub 2010 Sep 15. Mol Endocrinol. 2010. PMID: 20843941 Free PMC article.

10

Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells.

Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. Isaac R, et al. J Biol Chem. 2013 Feb 22;288(8):5682-93. doi: 10.1074/jbc.M112.408641. Epub 2012 Dec 28. J Biol Chem. 2013. PMID: 23275337 Free PMC article.

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