Laporte SA - Search Results

1

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.

Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, Bouvier M. Beautrait A, et al. Among authors: laporte sa. Nat Commun. 2017 Apr 18;8:15054. doi: 10.1038/ncomms15054. Nat Commun. 2017. PMID: 28416805 Free PMC article.

2

Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex.

Fessart D, Simaan M, Zimmerman B, Comeau J, Hamdan FF, Wiseman PW, Bouvier M, Laporte SA. Fessart D, et al. Among authors: laporte sa. J Cell Sci. 2007 May 15;120(Pt 10):1723-32. doi: 10.1242/jcs.03444. Epub 2007 Apr 24. J Cell Sci. 2007. PMID: 17456551

3

Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.

Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier M. Hamdan FF, et al. Among authors: laporte sa. J Biol Chem. 2007 Oct 5;282(40):29089-100. doi: 10.1074/jbc.M700577200. Epub 2007 Aug 3. J Biol Chem. 2007. PMID: 17675294 Free article.

4

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway.

Zimmerman B, Simaan M, Lee MH, Luttrell LM, Laporte SA. Zimmerman B, et al. Among authors: laporte sa. Cell Signal. 2009 Jan;21(1):103-10. doi: 10.1016/j.cellsig.2008.09.013. Epub 2008 Oct 1. Cell Signal. 2009. PMID: 18938240

5

A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.

Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA. Goupil E, et al. Among authors: laporte sa. J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551320 Free PMC article.

6

Role of ßarrestins in bradykinin B2 receptor-mediated signalling.

Zimmerman B, Simaan M, Akoume MY, Houri N, Chevallier S, Séguéla P, Laporte SA. Zimmerman B, et al. Among authors: laporte sa. Cell Signal. 2011 Apr;23(4):648-59. doi: 10.1016/j.cellsig.2010.11.016. Epub 2010 Dec 8. Cell Signal. 2011. PMID: 21145390

7

Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality.

Béliveau F, Brulé C, Désilets A, Zimmerman B, Laporte SA, Lavoie CL, Leduc R. Béliveau F, et al. Among authors: laporte sa. J Biol Chem. 2011 Aug 19;286(33):29035-29043. doi: 10.1074/jbc.M111.223461. Epub 2011 Jul 1. J Biol Chem. 2011. PMID: 21724843 Free PMC article.

8

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs.

Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA. Zimmerman B, et al. Among authors: laporte sa. Sci Signal. 2012 Apr 24;5(221):ra33. doi: 10.1126/scisignal.2002522. Sci Signal. 2012. PMID: 22534132

9

Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK.

Goupil E, Wisehart V, Khoury E, Zimmerman B, Jaffal S, Hébert TE, Laporte SA. Goupil E, et al. Among authors: laporte sa. Mol Endocrinol. 2012 Jul;26(7):1189-202. doi: 10.1210/me.2011-1245. Epub 2012 May 25. Mol Endocrinol. 2012. PMID: 22638073 Free PMC article.

10

GPCR heterodimers: asymmetries in ligand binding and signalling output offer new targets for drug discovery.

Goupil E, Laporte SA, Hébert TE. Goupil E, et al. Among authors: laporte sa. Br J Pharmacol. 2013 Mar;168(5):1101-3. doi: 10.1111/bph.12040. Br J Pharmacol. 2013. PMID: 23121476 Free PMC article.

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