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Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell.
Robison AJ, Vialou V, Mazei-Robison M, Feng J, Kourrich S, Collins M, Wee S, Koob G, Turecki G, Neve R, Thomas M, Nestler EJ. Robison AJ, et al. Among authors: neve r. J Neurosci. 2013 Mar 6;33(10):4295-307. doi: 10.1523/JNEUROSCI.5192-12.2013. J Neurosci. 2013. PMID: 23467346 Free PMC article.
SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens.
Ferguson D, Shao N, Heller E, Feng J, Neve R, Kim HD, Call T, Magazu S, Shen L, Nestler EJ. Ferguson D, et al. Among authors: neve r. J Neurosci. 2015 Feb 18;35(7):3100-11. doi: 10.1523/JNEUROSCI.4012-14.2015. J Neurosci. 2015. PMID: 25698746 Free PMC article.
ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.
Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, Golden SA, Gleason K, Russo SJ, Andrews S, Neve R, Kennedy PJ, Maze I, Dietz DM, Allis CD, Turecki G, Varga-Weisz P, Tamminga C, Shen L, Nestler EJ. Sun H, et al. Among authors: neve r. Nat Med. 2015 Oct;21(10):1146-53. doi: 10.1038/nm.3939. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390241 Free PMC article.
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens.
LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, Noonan MA, Ren Y, Eisch AJ, Bolaños CA, Kabbaj M, Xiao G, Neve RL, Hurd YL, Oosting RS, Fan G, Morrison JH, Nestler EJ. LaPlant Q, et al. Nat Neurosci. 2010 Sep;13(9):1137-43. doi: 10.1038/nn.2619. Epub 2010 Aug 22. Nat Neurosci. 2010. PMID: 20729844 Free PMC article.
Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons.
Dietz DM, Sun H, Lobo MK, Cahill ME, Chadwick B, Gao V, Koo JW, Mazei-Robison MS, Dias C, Maze I, Damez-Werno D, Dietz KC, Scobie KN, Ferguson D, Christoffel D, Ohnishi Y, Hodes GE, Zheng Y, Neve RL, Hahn KM, Russo SJ, Nestler EJ. Dietz DM, et al. Nat Neurosci. 2012 Jun;15(6):891-6. doi: 10.1038/nn.3094. Nat Neurosci. 2012. PMID: 22522400 Free PMC article.
515 results