Lim KL - Search Results

1

Genetic or pharmacological activation of the Drosophila PGC-1α ortholog spargel rescues the disease phenotypes of genetic models of Parkinson's disease.

Ng CH, Basil AH, Hang L, Tan R, Goh KL, O'Neill S, Zhang X, Yu F, Lim KL. Ng CH, et al. Among authors: lim kl. Neurobiol Aging. 2017 Jul;55:33-37. doi: 10.1016/j.neurobiolaging.2017.03.017. Epub 2017 Mar 18. Neurobiol Aging. 2017. PMID: 28407521 Free article.

2

Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?

Lim KL, Dawson VL, Dawson TM. Lim KL, et al. Neurobiol Aging. 2006 Apr;27(4):524-9. doi: 10.1016/j.neurobiolaging.2005.07.023. Epub 2005 Oct 6. Neurobiol Aging. 2006. PMID: 16213628 Review.

3

Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.

Wang C, Lu R, Ouyang X, Ho MW, Chia W, Yu F, Lim KL. Wang C, et al. Among authors: lim kl. J Neurosci. 2007 Aug 8;27(32):8563-70. doi: 10.1523/JNEUROSCI.0218-07.2007. J Neurosci. 2007. PMID: 17687034 Free PMC article.

4

Role of the ubiquitin proteasome system in Parkinson's disease.

Lim KL, Tan JM. Lim KL, et al. BMC Biochem. 2007 Nov 22;8 Suppl 1(Suppl 1):S13. doi: 10.1186/1471-2091-8-S1-S13. BMC Biochem. 2007. PMID: 18047737 Free PMC article. Review.

5

Genetic models of Parkinson disease.

Lim KL, Ng CH. Lim KL, et al. Biochim Biophys Acta. 2009 Jul;1792(7):604-15. doi: 10.1016/j.bbadis.2008.10.005. Epub 2008 Oct 22. Biochim Biophys Acta. 2009. PMID: 19000757 Free article. Review.

6

Protein misfolding and aggregation in Parkinson's disease.

Tan JM, Wong ES, Lim KL. Tan JM, et al. Among authors: lim kl. Antioxid Redox Signal. 2009 Sep;11(9):2119-34. doi: 10.1089/ars.2009.2490. Antioxid Redox Signal. 2009. PMID: 19243238 Review.

7

Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.

Ng CH, Mok SZ, Koh C, Ouyang X, Fivaz ML, Tan EK, Dawson VL, Dawson TM, Yu F, Lim KL. Ng CH, et al. Among authors: lim kl. J Neurosci. 2009 Sep 9;29(36):11257-62. doi: 10.1523/JNEUROSCI.2375-09.2009. J Neurosci. 2009. PMID: 19741132 Free PMC article.

8

AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease.

Ng CH, Guan MS, Koh C, Ouyang X, Yu F, Tan EK, O'Neill SP, Zhang X, Chung J, Lim KL. Ng CH, et al. Among authors: lim kl. J Neurosci. 2012 Oct 10;32(41):14311-7. doi: 10.1523/JNEUROSCI.0499-12.2012. J Neurosci. 2012. PMID: 23055502 Free PMC article.

9

Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila.

Angeles DC, Ho P, Chua LL, Wang C, Yap YW, Ng C, Zhou Zd, Lim KL, Wszolek ZK, Wang HY, Tan EK. Angeles DC, et al. Among authors: lim kl. Hum Mol Genet. 2014 Jun 15;23(12):3157-65. doi: 10.1093/hmg/ddu026. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24459295 Free PMC article.

10

Endocytic pathways downregulate the L1-type cell adhesion molecule neuroglian to promote dendrite pruning in Drosophila.

Zhang H, Wang Y, Wong JJ, Lim KL, Liou YC, Wang H, Yu F. Zhang H, et al. Among authors: lim kl. Dev Cell. 2014 Aug 25;30(4):463-78. doi: 10.1016/j.devcel.2014.06.014. Dev Cell. 2014. PMID: 25158855 Free article.

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