Abbott DW - Search Results

1

Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.

Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW. Chirieleison SM, et al. Among authors: abbott dw. J Biol Chem. 2017 Jun 9;292(23):9666-9679. doi: 10.1074/jbc.M117.781500. Epub 2017 Apr 12. J Biol Chem. 2017. PMID: 28404814 Free PMC article.

2

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA. Yang Y, et al. J Biol Chem. 2007 Dec 14;282(50):36223-9. doi: 10.1074/jbc.M703079200. Epub 2007 Oct 18. J Biol Chem. 2007. PMID: 17947236 Free article.

3

ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.

Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW. Tao M, et al. Among authors: abbott dw. Curr Biol. 2009 Aug 11;19(15):1255-63. doi: 10.1016/j.cub.2009.06.038. Epub 2009 Jul 9. Curr Biol. 2009. PMID: 19592251 Free PMC article.

4

A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.

Marinis JM, Homer CR, McDonald C, Abbott DW. Marinis JM, et al. Among authors: abbott dw. J Biol Chem. 2011 Jan 21;286(3):1938-50. doi: 10.1074/jbc.M110.189308. Epub 2010 Nov 19. J Biol Chem. 2011. PMID: 21097508 Free PMC article.

5

Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease.

Tigno-Aranjuez JT, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Biochim Biophys Acta. 2012 Nov;1823(11):2022-8. doi: 10.1016/j.bbamcr.2012.03.017. Epub 2012 Apr 11. Biochim Biophys Acta. 2012. PMID: 22522061 Free PMC article. Review.

6

IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.

Marinis JM, Hutti JE, Homer CR, Cobb BA, Cantley LC, McDonald C, Abbott DW. Marinis JM, et al. Among authors: abbott dw. Mol Cell Biol. 2012 Jul;32(13):2479-89. doi: 10.1128/MCB.00106-12. Epub 2012 Apr 30. Mol Cell Biol. 2012. PMID: 22547678 Free PMC article.

7

A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.

Tigno-Aranjuez JT, Bai X, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Mol Cell Biol. 2013 Jan;33(1):146-58. doi: 10.1128/MCB.01049-12. Epub 2012 Oct 29. Mol Cell Biol. 2013. PMID: 23109427 Free PMC article.

8

RIP2 activity in inflammatory disease and implications for novel therapeutics.

Jun JC, Cominelli F, Abbott DW. Jun JC, et al. Among authors: abbott dw. J Leukoc Biol. 2013 Nov;94(5):927-32. doi: 10.1189/jlb.0213109. Epub 2013 Jun 21. J Leukoc Biol. 2013. PMID: 23794710 Free PMC article. Review.

9

In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.

Tigno-Aranjuez JT, Benderitter P, Rombouts F, Deroose F, Bai X, Mattioli B, Cominelli F, Pizarro TT, Hoflack J, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. J Biol Chem. 2014 Oct 24;289(43):29651-64. doi: 10.1074/jbc.M114.591388. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213858 Free PMC article.

10

An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.

Perez JM, Chirieleison SM, Abbott DW. Perez JM, et al. Among authors: abbott dw. Cell Rep. 2015 Jul 28;12(4):537-44. doi: 10.1016/j.celrep.2015.06.050. Epub 2015 Jul 16. Cell Rep. 2015. PMID: 26190110 Free PMC article.

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