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YAP-mediated mechanotransduction determines the podocyte's response to damage.
Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B. Rinschen MM, et al. Among authors: kruger m. Sci Signal. 2017 Apr 11;10(474):eaaf8165. doi: 10.1126/scisignal.aaf8165. Sci Signal. 2017. PMID: 28400537
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks.
Boerries M, Grahammer F, Eiselein S, Buck M, Meyer C, Goedel M, Bechtel W, Zschiedrich S, Pfeifer D, Laloë D, Arrondel C, Gonçalves S, Krüger M, Harvey SJ, Busch H, Dengjel J, Huber TB. Boerries M, et al. Among authors: kruger m. Kidney Int. 2013 Jun;83(6):1052-64. doi: 10.1038/ki.2012.487. Epub 2013 Jan 30. Kidney Int. 2013. PMID: 23364521 Free article.
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
Rinschen MM, Palygin O, El-Meanawy A, Domingo-Almenara X, Palermo A, Dissanayake LV, Golosova D, Schafroth MA, Guijas C, Demir F, Jaegers J, Gliozzi ML, Xue J, Hoehne M, Benzing T, Kok BP, Saez E, Bleich M, Himmerkus N, Weisz OA, Cravatt BF, Krüger M, Benton HP, Siuzdak G, Staruschenko A. Rinschen MM, et al. Among authors: kruger m. Nat Commun. 2022 Jul 14;13(1):4099. doi: 10.1038/s41467-022-31670-0. Nat Commun. 2022. PMID: 35835746 Free PMC article.
Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway.
Späth MR, Hoyer-Allo KJR, Seufert L, Höhne M, Lucas C, Bock T, Isermann L, Brodesser S, Lackmann JW, Kiefer K, Koehler FC, Bohl K, Ignarski M, Schiller P, Johnsen M, Kubacki T, Grundmann F, Benzing T, Trifunovic A, Krüger M, Schermer B, Burst V, Müller RU. Späth MR, et al. Among authors: kruger m. J Am Soc Nephrol. 2023 May 1;34(5):772-792. doi: 10.1681/ASN.0000000000000087. Epub 2023 Feb 9. J Am Soc Nephrol. 2023. PMID: 36758124 Free PMC article.
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M. Lim R, et al. Among authors: kruger m. Science. 2019 Apr 12;364(6436):188-193. doi: 10.1126/science.aat0778. Science. 2019. PMID: 30975888
Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies.
Izquierdo E, Vorholt D, Blakemore S, Sackey B, Nolte JL, Barbarino V, Schmitz J, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch M, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel L, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP. Izquierdo E, et al. Among authors: kruger m. Blood. 2022 Jun 23;139(25):3617-3629. doi: 10.1182/blood.2021014007. Blood. 2022. PMID: 35344582 Free article.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D. Sen A, et al. Among authors: kruger m. Nat Commun. 2022 Nov 7;13(1):6704. doi: 10.1038/s41467-022-34205-9. Nat Commun. 2022. PMID: 36344526 Free PMC article.
Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition.
Beielstein AC, Izquierdo E, Blakemore S, Nickel N, Michalik M, Chawan S, Brinker R, Bartel HH, Vorholt D, Albert L, Nolte JL, Linke R, Costa Picossi CR, Sáiz J, Picard F, Florin A, Meinel J, Büttner R, Diefenhardt P, Brähler S, Villaseñor A, Winkels H, Hallek M, Krüger M, Barbas C, Pallasch CP. Beielstein AC, et al. Among authors: kruger m. Cell Rep Med. 2024 Dec 17;5(12):101830. doi: 10.1016/j.xcrm.2024.101830. Epub 2024 Nov 26. Cell Rep Med. 2024. PMID: 39603243 Free article.
1,623 results