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222 results

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Page 1
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.
Vicente Miranda H, Szego ÉM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF. Vicente Miranda H, et al. Among authors: lashuel ha. Brain. 2017 May 1;140(5):1399-1419. doi: 10.1093/brain/awx056. Brain. 2017. PMID: 28398476
Structural properties of pore-forming oligomers of alpha-synuclein.
Kim HY, Cho MK, Kumar A, Maier E, Siebenhaar C, Becker S, Fernandez CO, Lashuel HA, Benz R, Lange A, Zweckstetter M. Kim HY, et al. Among authors: lashuel ha. J Am Chem Soc. 2009 Dec 2;131(47):17482-9. doi: 10.1021/ja9077599. J Am Chem Soc. 2009. PMID: 19888725 Free article.
Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity.
Di Giovanni S, Eleuteri S, Paleologou KE, Yin G, Zweckstetter M, Carrupt PA, Lashuel HA. Di Giovanni S, et al. Among authors: lashuel ha. J Biol Chem. 2010 May 14;285(20):14941-14954. doi: 10.1074/jbc.M109.080390. Epub 2010 Feb 11. J Biol Chem. 2010. PMID: 20150427 Free PMC article.
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
Paleologou KE, Oueslati A, Shakked G, Rospigliosi CC, Kim HY, Lamberto GR, Fernandez CO, Schmid A, Chegini F, Gai WP, Chiappe D, Moniatte M, Schneider BL, Aebischer P, Eliezer D, Zweckstetter M, Masliah E, Lashuel HA. Paleologou KE, et al. Among authors: lashuel ha. J Neurosci. 2010 Mar 3;30(9):3184-98. doi: 10.1523/JNEUROSCI.5922-09.2010. J Neurosci. 2010. PMID: 20203178 Free PMC article.
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action.
Ouertatani-Sakouhi H, El-Turk F, Fauvet B, Cho MK, Pinar Karpinar D, Le Roy D, Dewor M, Roger T, Bernhagen J, Calandra T, Zweckstetter M, Lashuel HA. Ouertatani-Sakouhi H, et al. Among authors: lashuel ha. J Biol Chem. 2010 Aug 20;285(34):26581-98. doi: 10.1074/jbc.M110.113951. Epub 2010 Jun 1. J Biol Chem. 2010. PMID: 20516071 Free PMC article.
Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125.
Hejjaoui M, Butterfield S, Fauvet B, Vercruysse F, Cui J, Dikiy I, Prudent M, Olschewski D, Zhang Y, Eliezer D, Lashuel HA. Hejjaoui M, et al. Among authors: lashuel ha. J Am Chem Soc. 2012 Mar 21;134(11):5196-210. doi: 10.1021/ja210866j. Epub 2012 Mar 13. J Am Chem Soc. 2012. PMID: 22339654 Free PMC article.
222 results