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An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation.
Roberts AR, Vecellio M, Chen L, Ridley A, Cortes A, Knight JC, Bowness P, Cohen CJ, Wordsworth BP. Roberts AR, et al. Among authors: vecellio m. Ann Rheum Dis. 2016 Dec;75(12):2150-2156. doi: 10.1136/annrheumdis-2015-208640. Epub 2016 Feb 25. Ann Rheum Dis. 2016. PMID: 26916345 Free PMC article.
The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis.
Watts L, Karaderi T, Roberts A, Appleton L, Wordsworth T, Cohen C, Wordsworth P, Vecellio M. Watts L, et al. Among authors: vecellio m. Genes Immun. 2019 Feb;20(2):167-171. doi: 10.1038/s41435-018-0017-0. Epub 2018 Mar 10. Genes Immun. 2019. PMID: 29535371
46 results