Weir GC - Search Results

1

β Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance.

Aguayo-Mazzucato C, van Haaren M, Mruk M, Lee TB Jr, Crawford C, Hollister-Lock J, Sullivan BA, Johnson JW, Ebrahimi A, Dreyfuss JM, Van Deursen J, Weir GC, Bonner-Weir S. Aguayo-Mazzucato C, et al. Among authors: weir gc. Cell Metab. 2017 Apr 4;25(4):898-910.e5. doi: 10.1016/j.cmet.2017.03.015. Cell Metab. 2017. PMID: 28380379 Free PMC article.

2

beta-cell adaptation to hyperglycemia.

Laybutt R, Hasenkamp W, Groff A, Grey S, Jonas JC, Kaneto H, Sharma A, Bonner-Weir S, Weir G. Laybutt R, et al. Diabetes. 2001 Feb;50 Suppl 1:S180-1. doi: 10.2337/diabetes.50.2007.s180. Diabetes. 2001. PMID: 11272186 No abstract available.

3

Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells.

Kaneto H, Suzuma K, Sharma A, Bonner-Weir S, King GL, Weir GC. Kaneto H, et al. Among authors: weir gc. J Biol Chem. 2002 Feb 1;277(5):3680-5. doi: 10.1074/jbc.M109647200. Epub 2001 Nov 19. J Biol Chem. 2002. PMID: 11714718 Free article.

4

Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.

Laybutt DR, Sharma A, Sgroi DC, Gaudet J, Bonner-Weir S, Weir GC. Laybutt DR, et al. Among authors: weir gc. J Biol Chem. 2002 Mar 29;277(13):10912-21. doi: 10.1074/jbc.M111751200. Epub 2002 Jan 8. J Biol Chem. 2002. PMID: 11782487 Free article.

5

Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation.

Kaneto H, Sharma A, Suzuma K, Laybutt DR, Xu G, Bonner-Weir S, Weir GC. Kaneto H, et al. Among authors: weir gc. J Biol Chem. 2002 Apr 12;277(15):12998-3006. doi: 10.1074/jbc.M111148200. Epub 2002 Jan 17. J Biol Chem. 2002. PMID: 11799123 Free article.

6

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia.

Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Laybutt DR, et al. Among authors: weir gc. Diabetes. 2002 Feb;51(2):413-23. doi: 10.2337/diabetes.51.2.413. Diabetes. 2002. PMID: 11812749

7

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression.

Kaneto H, Xu G, Fujii N, Kim S, Bonner-Weir S, Weir GC. Kaneto H, et al. Among authors: weir gc. J Biol Chem. 2002 Aug 16;277(33):30010-8. doi: 10.1074/jbc.M202066200. Epub 2002 May 14. J Biol Chem. 2002. PMID: 12011047 Free article.

8

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.

Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S. Laybutt DR, et al. Among authors: weir gc. Diabetes. 2002 Jun;51(6):1793-804. doi: 10.2337/diabetes.51.6.1793. Diabetes. 2002. PMID: 12031967

9

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.

Laybutt DR, Glandt M, Xu G, Ahn YB, Trivedi N, Bonner-Weir S, Weir GC. Laybutt DR, et al. Among authors: weir gc. J Biol Chem. 2003 Jan 31;278(5):2997-3005. doi: 10.1074/jbc.M210581200. Epub 2002 Nov 15. J Biol Chem. 2003. PMID: 12438314 Free article.

10

Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice.

Omer A, Duvivier-Kali VF, Trivedi N, Wilmot K, Bonner-Weir S, Weir GC. Omer A, et al. Among authors: weir gc. Diabetes. 2003 Jan;52(1):69-75. doi: 10.2337/diabetes.52.1.69. Diabetes. 2003. PMID: 12502495

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