DeForrest JM - Search Results

1

Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.

Krapcho J, Turk C, Cushman DW, Powell JR, DeForrest JM, Spitzmiller ER, Karanewsky DS, Duggan M, Rovnyak G, Schwartz J, et al. Krapcho J, et al. Among authors: deforrest jm. J Med Chem. 1988 Jun;31(6):1148-60. doi: 10.1021/jm00401a014. J Med Chem. 1988. PMID: 2836590

2

Ceranapril (SQ 29,852), an orally active inhibitor of angiotensin converting enzyme (ACE).

DeForrest JM, Waldron TL, Harvey C, Scalese R, Hammerstone S, Powell JR, Karanewsky D. DeForrest JM, et al. J Cardiovasc Pharmacol. 1990 Jul;16(1):121-7. doi: 10.1097/00005344-199007000-00017. J Cardiovasc Pharmacol. 1990. PMID: 1696654

3

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogues of (S)-1-[6-amino-2 [[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline.

Karanewsky DS, Badia MC, Cushman DW, DeForrest JM, Dejneka T, Lee VG, Loots MJ, Petrillo EW. Karanewsky DS, et al. Among authors: deforrest jm. J Med Chem. 1990 May;33(5):1459-69. doi: 10.1021/jm00167a028. J Med Chem. 1990. PMID: 2329568

4

Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology.

DeForrest JM, Waldron TL, Harvey C, Scalese B, Rubin B, Powell JR, Petrillo EW, Cushman DW. DeForrest JM, et al. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6. doi: 10.1097/00005344-198911000-00009. J Cardiovasc Pharmacol. 1989. PMID: 2481187

5

Preclinical pharmacology of zofenopril, an inhibitor of angiotensin I converting enzyme.

DeForrest JM, Waldron TL, Krapcho J, Turk C, Rubin B, Powell JR, Cushman DW, Petrillo EW. DeForrest JM, et al. J Cardiovasc Pharmacol. 1989 Jun;13(6):887-94. doi: 10.1097/00005344-198906000-00011. J Cardiovasc Pharmacol. 1989. PMID: 2484083

6

Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE).

Cushman DW, Wang FL, Fung WC, Grover GJ, Harvey CM, Scalese RJ, Mitch SL, DeForrest JM. Cushman DW, et al. Among authors: deforrest jm. Br J Clin Pharmacol. 1989;28 Suppl 2(Suppl 2):115S-130S; discussion 130S-131S. doi: 10.1111/j.1365-2125.1989.tb03587.x. Br J Clin Pharmacol. 1989. PMID: 2557876 Free PMC article.

7

Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs.

Cushman DW, Wang FL, Fung WC, Harvey CM, DeForrest JM. Cushman DW, et al. Among authors: deforrest jm. Am J Hypertens. 1989 Apr;2(4):294-306. doi: 10.1093/ajh/2.4.294. Am J Hypertens. 1989. PMID: 2706094

8

Ketomethylureas. A new class of angiotensin converting enzyme inhibitors.

Natarajan S, Gordon EM, Sabo EF, Godfrey JD, Weller HN, Pluscec J, Rom MB, Engebrecht J, Cushman DW, Deforrest JM, et al. Natarajan S, et al. Among authors: deforrest jm. J Enzyme Inhib. 1988;2(2):91-7. doi: 10.3109/14756368809040715. J Enzyme Inhib. 1988. PMID: 3236070

9

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L -proline a novel orally active inhibitor of ACE.

Karanewsky DS, Badia MC, Cushman DW, DeForrest JM, Dejneka T, Loots MJ, Perri MG, Petrillo EW Jr, Powell JR. Karanewsky DS, et al. Among authors: deforrest jm. J Med Chem. 1988 Jan;31(1):204-12. doi: 10.1021/jm00396a033. J Med Chem. 1988. PMID: 3336020

10

Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models.

DeForrest JM, Waldron TL, Harvey C, Scalese B, Mitch S, Powell JR, Petrillo W, Cushman DW. DeForrest JM, et al. J Cardiovasc Pharmacol. 1990 Jul;16(1):139-46. doi: 10.1097/00005344-199007000-00019. J Cardiovasc Pharmacol. 1990. PMID: 1696656

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