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The cytotoxic effects of VE-3N, a novel 1,4-dihydropyridine derivative, involve the mitochondrial bioenergetic disruption via uncoupling mechanisms.
Marín-Prida J, Pardo Andreu GL, Rossignoli CP, Durruthy MG, Rodríguez EO, Reyes YV, Acosta RF, Uyemura SA, Alberici LC. Marín-Prida J, et al. Among authors: durruthy mg. Toxicol In Vitro. 2017 Aug;42:21-30. doi: 10.1016/j.tiv.2017.03.011. Epub 2017 Mar 29. Toxicol In Vitro. 2017. PMID: 28363597 Free article.
Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays.
Ramos P, Schmitz M, Gama S, Portantiolo A, Durruthy MG, de Souza Votto AP, Cornetet LR, Dos Santos Machado K, Werhli A, Tonel MZ, Fagan SB, Yunes JS, Monserrat JM. Ramos P, et al. Among authors: durruthy mg. Toxicology. 2018 Jan 15;393:171-184. doi: 10.1016/j.tox.2017.11.004. Epub 2017 Nov 8. Toxicology. 2018. PMID: 29128272
In vitro and in silico protein corona formation evaluation of curcumin and capsaicin loaded-solid lipid nanoparticles.
Nishihira VSK, Rubim AM, Brondani M, Dos Santos JT, Pohl AR, Friedrich JF, de Lara JD, Nunes CM, Feksa LR, Simão E, de Almeida Vaucher R, Durruthy MG, Laporta LV, Rech VC. Nishihira VSK, et al. Among authors: durruthy mg. Toxicol In Vitro. 2019 Dec;61:104598. doi: 10.1016/j.tiv.2019.104598. Epub 2019 Jul 9. Toxicol In Vitro. 2019. PMID: 31299314