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The cytotoxic effects of VE-3N, a novel 1,4-dihydropyridine derivative, involve the mitochondrial bioenergetic disruption via uncoupling mechanisms.
Marín-Prida J, Pardo Andreu GL, Rossignoli CP, Durruthy MG, Rodríguez EO, Reyes YV, Acosta RF, Uyemura SA, Alberici LC. Marín-Prida J, et al. Among authors: acosta rf. Toxicol In Vitro. 2017 Aug;42:21-30. doi: 10.1016/j.tiv.2017.03.011. Epub 2017 Mar 29. Toxicol In Vitro. 2017. PMID: 28363597 Free article.