Hoffman BE - Search Results

1

Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity.

Krotova K, Marek GW, Wang RL, Aslanidi G, Hoffman BE, Khodayari N, Rouhani FN, Brantly ML. Krotova K, et al. Among authors: hoffman be. Am J Respir Cell Mol Biol. 2017 Aug;57(2):238-247. doi: 10.1165/rcmb.2016-0366OC. Am J Respir Cell Mol Biol. 2017. PMID: 28362108 Free PMC article.

2

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

Markusic DM, Herzog RW, Aslanidi GV, Hoffman BE, Li B, Li M, Jayandharan GR, Ling C, Zolotukhin I, Ma W, Zolotukhin S, Srivastava A, Zhong L. Markusic DM, et al. Among authors: hoffman be. Mol Ther. 2010 Dec;18(12):2048-56. doi: 10.1038/mt.2010.172. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736929 Free PMC article.

3

Reprogramming Immune Response With Capsid-Optimized AAV6 Vectors for Immunotherapy of Cancer.

Pandya M, Britt K, Hoffman B, Ling C, Aslanidi GV. Pandya M, et al. J Immunother. 2015 Sep;38(7):292-8. doi: 10.1097/CJI.0000000000000093. J Immunother. 2015. PMID: 26261893 Free PMC article.

4

Impact of the underlying mutation and the route of vector administration on immune responses to factor IX in gene therapy for hemophilia B.

Cao O, Hoffman BE, Moghimi B, Nayak S, Cooper M, Zhou S, Ertl HC, High KA, Herzog RW. Cao O, et al. Among authors: hoffman be. Mol Ther. 2009 Oct;17(10):1733-42. doi: 10.1038/mt.2009.159. Epub 2009 Jul 14. Mol Ther. 2009. PMID: 19603001 Free PMC article.

5

Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors.

Hoffman BE, Herzog RW. Hoffman BE, et al. Mol Ther. 2013 Sep;21(9):1648-50. doi: 10.1038/mt.2013.176. Mol Ther. 2013. PMID: 24008618 Free PMC article. No abstract available.

6

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis.

Keeler GD, Kumar S, Palaschak B, Silverberg EL, Markusic DM, Jones NT, Hoffman BE. Keeler GD, et al. Among authors: hoffman be. Mol Ther. 2018 Jan 3;26(1):173-183. doi: 10.1016/j.ymthe.2017.09.001. Epub 2017 Sep 21. Mol Ther. 2018. PMID: 28943274 Free PMC article.

7

The Balance between CD8⁺ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.

Kumar SRP, Hoffman BE, Terhorst C, de Jong YP, Herzog RW. Kumar SRP, et al. Among authors: hoffman be. Mol Ther. 2017 Apr 5;25(4):880-891. doi: 10.1016/j.ymthe.2017.02.014. Epub 2017 Mar 9. Mol Ther. 2017. PMID: 28284982 Free PMC article.

8

Type I IFN Sensing by cDCs and CD4⁺ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8⁺ T Cells.

Shirley JL, Keeler GD, Sherman A, Zolotukhin I, Markusic DM, Hoffman BE, Morel LM, Wallet MA, Terhorst C, Herzog RW. Shirley JL, et al. Among authors: hoffman be. Mol Ther. 2020 Mar 4;28(3):758-770. doi: 10.1016/j.ymthe.2019.11.011. Epub 2019 Nov 15. Mol Ther. 2020. PMID: 31780366 Free PMC article.

9

Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer.

Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Hoffman BE, et al. Mol Ther. 2011 Jul;19(7):1263-72. doi: 10.1038/mt.2011.33. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386826 Free PMC article.

10

Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid.

Vercauteren K, Hoffman BE, Zolotukhin I, Keeler GD, Xiao JW, Basner-Tschakarjan E, High KA, Ertl HC, Rice CM, Srivastava A, de Jong YP, Herzog RW. Vercauteren K, et al. Among authors: hoffman be. Mol Ther. 2016 Jun;24(6):1042-1049. doi: 10.1038/mt.2016.61. Epub 2016 Mar 29. Mol Ther. 2016. PMID: 27019999 Free PMC article.

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