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Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.
Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: pearson jt. JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271. JCI Insight. 2017. PMID: 28352650 Free PMC article.
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.
Furtado MB, Wilmanns JC, Chandran A, Tonta M, Biben C, Eichenlaub M, Coleman HA, Berger S, Bouveret R, Singh R, Harvey RP, Ramialison M, Pearson JT, Parkington HC, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: pearson jt. Differentiation. 2016 Jan-Mar;91(1-3):29-41. doi: 10.1016/j.diff.2015.12.003. Epub 2016 Feb 17. Differentiation. 2016. PMID: 26897459
Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease.
Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW. Wilmanns JC, et al. Among authors: pearson jt. Mol Metab. 2019 Feb;20:102-114. doi: 10.1016/j.molmet.2018.11.002. Epub 2018 Nov 15. Mol Metab. 2019. PMID: 30482476 Free PMC article.
Diffusion Tensor Imaging Colour Mapping Threshold for Identification of Ventilation-Induced Brain Injury after Intrauterine Inflammation in Preterm Lambs.
Alahmari DM, Skiöld B, Barton SK, Nitsos I, McDonald C, Miller SL, Zahra V, Galinsky R, Wu Q, Farrell MJ, Moss TJ, Hooper SB, Pearson JT, Polglase GR. Alahmari DM, et al. Among authors: pearson jt. Front Pediatr. 2017 Apr 5;5:70. doi: 10.3389/fped.2017.00070. eCollection 2017. Front Pediatr. 2017. PMID: 28424764 Free PMC article.
β2-Adrenergic receptor-dependent attenuation of hypoxic pulmonary vasoconstriction prevents progression of pulmonary arterial hypertension in intermittent hypoxic rats.
Nagai H, Kuwahira I, Schwenke DO, Tsuchimochi H, Nara A, Inagaki T, Ogura S, Fujii Y, Umetani K, Shimosawa T, Yoshida K, Pearson JT, Uemura K, Shirai M. Nagai H, et al. Among authors: pearson jt. PLoS One. 2014 Oct 28;9(10):e110693. doi: 10.1371/journal.pone.0110693. eCollection 2014. PLoS One. 2014. PMID: 25350545 Free PMC article.
Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications.
Saw EL, Pearson JT, Schwenke DO, Munasinghe PE, Tsuchimochi H, Rawal S, Coffey S, Davis P, Bunton R, Van Hout I, Kai Y, Williams MJA, Kakinuma Y, Fronius M, Katare R. Saw EL, et al. Among authors: pearson jt. Cardiovasc Diabetol. 2021 Feb 22;20(1):50. doi: 10.1186/s12933-021-01231-8. Cardiovasc Diabetol. 2021. PMID: 33618724 Free PMC article.
Cell-sheet therapy with omentopexy promotes arteriogenesis and improves coronary circulation physiology in failing heart.
Kainuma S, Miyagawa S, Fukushima S, Pearson J, Chen YC, Saito A, Harada A, Shiozaki M, Iseoka H, Watabe T, Watabe H, Horitsugi G, Ishibashi M, Ikeda H, Tsuchimochi H, Sonobe T, Fujii Y, Naito H, Umetani K, Shimizu T, Okano T, Kobayashi E, Daimon T, Ueno T, Kuratani T, Toda K, Takakura N, Hatazawa J, Shirai M, Sawa Y. Kainuma S, et al. Mol Ther. 2015 Feb;23(2):374-86. doi: 10.1038/mt.2014.225. Epub 2014 Nov 25. Mol Ther. 2015. PMID: 25421595 Free PMC article.
Using Synchrotron Radiation Imaging Techniques to Elucidate the Actions of Hexarelin in the Heart of Small Animal Models.
Waddingham MT, Tsuchimochi H, Sonobe T, Asano R, Jin H, Ow CPC, Schwenke DO, Katare R, Aoyama K, Umetani K, Hoshino M, Uesugi K, Shirai M, Ogo T, Pearson JT. Waddingham MT, et al. Among authors: pearson jt. Front Physiol. 2022 Jan 21;12:766818. doi: 10.3389/fphys.2021.766818. eCollection 2021. Front Physiol. 2022. PMID: 35126171 Free PMC article.
197 results