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Chemical screening identifies ATM as a target for alleviating senescence.
Nat Chem Biol. 2017 Jun;13(6):616-623. doi: 10.1038/nchembio.2342. Epub 2017 Mar 27.
Nat Chem Biol. 2017.
PMID: 28346404
Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome.
Kang HT, Park JT, Choi K, Choi HJC, Jung CW, Kim GR, Lee YS, Park SC.
Kang HT, et al. Among authors: choi hjc.
Aging Cell. 2017 Jun;16(3):541-550. doi: 10.1111/acel.12584. Epub 2017 Mar 19.
Aging Cell. 2017.
PMID: 28317242
Free PMC article.
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Disruption of nucleocytoplasmic trafficking as a cellular senescence driver.
Park JH, Ryu SJ, Kim BJ, Cho HJ, Park CH, Choi HJC, Jang EJ, Yang EJ, Hwang JA, Woo SH, Lee JH, Park JH, Choi KM, Kwon YY, Lee CK, Park JT, Cho SC, Lee YI, Lee SB, Han JA, Cho KA, Kim MS, Hwang D, Lee YS, Park SC.
Park JH, et al. Among authors: choi hjc.
Exp Mol Med. 2021 Jun;53(6):1092-1108. doi: 10.1038/s12276-021-00643-6. Epub 2021 Jun 29.
Exp Mol Med. 2021.
PMID: 34188179
Free PMC article.
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NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.
Choi HJ, Lin JR, Vannier JB, Slaats GG, Kile AC, Paulsen RD, Manning DK, Beier DR, Giles RH, Boulton SJ, Cimprich KA.
Choi HJ, et al.
Mol Cell. 2013 Aug 22;51(4):423-39. doi: 10.1016/j.molcel.2013.08.006.
Mol Cell. 2013.
PMID: 23973373
Free PMC article.
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