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A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.
Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ. Skorecki KL, et al. Among authors: alper sl. Nephrol Dial Transplant. 2018 Feb 1;33(2):323-330. doi: 10.1093/ndt/gfw451. Nephrol Dial Transplant. 2018. PMID: 28339911 Free PMC article.
Evolution of the primate trypanolytic factor APOL1.
Thomson R, Genovese G, Canon C, Kovacsics D, Higgins MK, Carrington M, Winkler CA, Kopp J, Rotimi C, Adeyemo A, Doumatey A, Ayodo G, Alper SL, Pollak MR, Friedman DJ, Raper J. Thomson R, et al. Among authors: alper sl. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2130-9. doi: 10.1073/pnas.1400699111. Epub 2014 May 7. Proc Natl Acad Sci U S A. 2014. PMID: 24808134 Free PMC article.
Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.
Nichols B, Jog P, Lee JH, Blackler D, Wilmot M, D'Agati V, Markowitz G, Kopp JB, Alper SL, Pollak MR, Friedman DJ. Nichols B, et al. Among authors: alper sl. Kidney Int. 2015 Feb;87(2):332-42. doi: 10.1038/ki.2014.270. Epub 2014 Aug 6. Kidney Int. 2015. PMID: 25100047 Free PMC article.
Copy Number Variation at the APOL1 Locus.
Ruchi R, Genovese G, Lee J, Charoonratana VT, Bernhardy AJ, Alper SL, Kopp JB, Thadhani R, Friedman DJ, Pollak MR. Ruchi R, et al. Among authors: alper sl. PLoS One. 2015 May 1;10(5):e0125410. doi: 10.1371/journal.pone.0125410. eCollection 2015. PLoS One. 2015. PMID: 25933006 Free PMC article.
APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.
Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S 3rd, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR. Olabisi OA, et al. Among authors: alper sl. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):830-7. doi: 10.1073/pnas.1522913113. Epub 2015 Dec 23. Proc Natl Acad Sci U S A. 2016. PMID: 26699492 Free PMC article.
377 results