Wang BC - Search Results

1

A role of the SAM domain in EphA2 receptor activation.

Shi X, Hapiak V, Zheng J, Muller-Greven J, Bowman D, Lingerak R, Buck M, Wang BC, Smith AW. Shi X, et al. Among authors: wang bc. Sci Rep. 2017 Mar 24;7:45084. doi: 10.1038/srep45084. Sci Rep. 2017. PMID: 28338017 Free PMC article.

2

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation.

Miao H, Burnett E, Kinch M, Simon E, Wang B. Miao H, et al. Nat Cell Biol. 2000 Feb;2(2):62-9. doi: 10.1038/35000008. Nat Cell Biol. 2000. PMID: 10655584

3

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway.

Miao H, Wei BR, Peehl DM, Li Q, Alexandrou T, Schelling JR, Rhim JS, Sedor JR, Burnett E, Wang B. Miao H, et al. Nat Cell Biol. 2001 May;3(5):527-30. doi: 10.1038/35074604. Nat Cell Biol. 2001. PMID: 11331884

4

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.

Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B. Guo H, et al. Cancer Res. 2006 Jul 15;66(14):7050-8. doi: 10.1158/0008-5472.CAN-06-0004. Cancer Res. 2006. PMID: 16849550

5

Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.

Himanen JP, Goldgur Y, Miao H, Myshkin E, Guo H, Buck M, Nguyen M, Rajashankar KR, Wang B, Nikolov DB. Himanen JP, et al. EMBO Rep. 2009 Jul;10(7):722-8. doi: 10.1038/embor.2009.91. Epub 2009 Jun 12. EMBO Rep. 2009. PMID: 19525919 Free PMC article.

6

EPHA2 is associated with age-related cortical cataract in mice and humans.

Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P, Miao H, Lee KE, Joshi T, Buck M, Chugha P, Bardenstein D, Klein AP, Bailey-Wilson JE, Gong X, Spector TD, Andrew T, Hammond CJ, Elston RC, Iyengar SK, Wang B. Jun G, et al. PLoS Genet. 2009 Jul;5(7):e1000584. doi: 10.1371/journal.pgen.1000584. Epub 2009 Jul 31. PLoS Genet. 2009. PMID: 19649315 Free PMC article.

7

NMR structure of a heterodimeric SAM:SAM complex: characterization and manipulation of EphA2 binding reveal new cellular functions of SHIP2.

Lee HJ, Hota PK, Chugha P, Guo H, Miao H, Zhang L, Kim SJ, Stetzik L, Wang BC, Buck M. Lee HJ, et al. Among authors: wang bc. Structure. 2012 Jan 11;20(1):41-55. doi: 10.1016/j.str.2011.11.013. Structure. 2012. PMID: 22244754 Free PMC article.

8

Binding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile α motif (SAM) domains.

Borthakur S, Lee H, Kim S, Wang BC, Buck M. Borthakur S, et al. Among authors: wang bc. J Biol Chem. 2014 Jul 11;289(28):19694-703. doi: 10.1074/jbc.M114.567602. Epub 2014 May 13. J Biol Chem. 2014. PMID: 24825902 Free PMC article.

9

Design and synthesis of small molecule agonists of EphA2 receptor.

Petty A, Idippily N, Bobba V, Geldenhuys WJ, Zhong B, Su B, Wang B. Petty A, et al. Eur J Med Chem. 2018 Jan 1;143:1261-1276. doi: 10.1016/j.ejmech.2017.10.026. Epub 2017 Oct 10. Eur J Med Chem. 2018. PMID: 29128116 Free PMC article.

10

A novel pH-dependent membrane peptide that binds to EphA2 and inhibits cell migration.

Alves DS, Westerfield JM, Shi X, Nguyen VP, Stefanski KM, Booth KR, Kim S, Morrell-Falvey J, Wang BC, Abel SM, Smith AW, Barrera FN. Alves DS, et al. Among authors: wang bc. Elife. 2018 Sep 17;7:e36645. doi: 10.7554/eLife.36645. Elife. 2018. PMID: 30222105 Free PMC article.

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