Rigby AC - Search Results

1

Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders.

Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A. Bezzerides VJ, et al. Among authors: rigby ac. Sci Rep. 2017 Mar 23;7(1):346. doi: 10.1038/s41598-017-00413-3. Sci Rep. 2017. PMID: 28336914 Free PMC article.

2

Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia.

Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM. Khedkar SA, et al. Among authors: rigby ac. Sci Rep. 2017 Aug 16;7(1):8427. doi: 10.1038/s41598-017-08670-y. Sci Rep. 2017. PMID: 28814738 Free PMC article.

3

Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation.

Khedkar SA, Sun X, Rigby AC, Feinberg MW. Khedkar SA, et al. Among authors: rigby ac. J Med Chem. 2015 Feb 12;58(3):1466-78. doi: 10.1021/jm5018187. Epub 2015 Feb 4. J Med Chem. 2015. PMID: 25581017 Free PMC article.

4

Successful applications of computer aided drug discovery: moving drugs from concept to the clinic.

Talele TT, Khedkar SA, Rigby AC. Talele TT, et al. Among authors: rigby ac. Curr Top Med Chem. 2010;10(1):127-41. doi: 10.2174/156802610790232251. Curr Top Med Chem. 2010. PMID: 19929824 Review.

5

Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.

Patil SP, Maki S, Khedkar SA, Rigby AC, Chan C. Patil SP, et al. Among authors: rigby ac. J Nat Prod. 2010 Jul 23;73(7):1196-202. doi: 10.1021/np900633j. J Nat Prod. 2010. PMID: 20553006 Free PMC article.

6

Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.

Thadhani R, Kisner T, Hagmann H, Bossung V, Noack S, Schaarschmidt W, Jank A, Kribs A, Cornely OA, Kreyssig C, Hemphill L, Rigby AC, Khedkar S, Lindner TH, Mallmann P, Stepan H, Karumanchi SA, Benzing T. Thadhani R, et al. Among authors: rigby ac. Circulation. 2011 Aug 23;124(8):940-50. doi: 10.1161/CIRCULATIONAHA.111.034793. Epub 2011 Aug 1. Circulation. 2011. PMID: 21810665 Clinical Trial.

7

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.

Gerald D, Adini I, Shechter S, Perruzzi C, Varnau J, Hopkins B, Kazerounian S, Kurschat P, Blachon S, Khedkar S, Bagchi M, Sherris D, Prendergast GC, Klagsbrun M, Stuhlmann H, Rigby AC, Nagy JA, Benjamin LE. Gerald D, et al. Among authors: rigby ac. Nat Commun. 2013;4:2824. doi: 10.1038/ncomms3824. Nat Commun. 2013. PMID: 24280686 Free PMC article.

8

Human SLC26A4/Pendrin STAS domain is a nucleotide-binding protein: Refolding and characterization for structural studies.

Sharma AK, Krieger T, Rigby AC, Zelikovic I, Alper SL. Sharma AK, et al. Among authors: rigby ac. Biochem Biophys Rep. 2016 Aug 26;8:184-191. doi: 10.1016/j.bbrep.2016.08.022. eCollection 2016 Dec. Biochem Biophys Rep. 2016. PMID: 28955955 Free PMC article.

9

In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.

Shen HC, Shanmugasundaram K, Simon NI, Cai C, Wang H, Chen S, Balk SP, Rigby AC. Shen HC, et al. Among authors: rigby ac. Mol Endocrinol. 2012 Nov;26(11):1836-46. doi: 10.1210/me.2012-1222. Epub 2012 Sep 28. Mol Endocrinol. 2012. PMID: 23023563 Free PMC article.

10

Critical role for the Ets transcription factor ELF-1 in the development of tumor angiogenesis.

Huang X, Brown C, Ni W, Maynard E, Rigby AC, Oettgen P. Huang X, et al. Among authors: rigby ac. Blood. 2006 Apr 15;107(8):3153-60. doi: 10.1182/blood-2005-08-3206. Epub 2005 Dec 13. Blood. 2006. PMID: 16352813 Free PMC article.

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