Khedkar SA - Search Results

1

Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders.

Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A. Bezzerides VJ, et al. Among authors: khedkar sa. Sci Rep. 2017 Mar 23;7(1):346. doi: 10.1038/s41598-017-00413-3. Sci Rep. 2017. PMID: 28336914 Free PMC article.

2

Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia.

Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM. Khedkar SA, et al. Sci Rep. 2017 Aug 16;7(1):8427. doi: 10.1038/s41598-017-08670-y. Sci Rep. 2017. PMID: 28814738 Free PMC article.

3

Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation.

Khedkar SA, Sun X, Rigby AC, Feinberg MW. Khedkar SA, et al. J Med Chem. 2015 Feb 12;58(3):1466-78. doi: 10.1021/jm5018187. Epub 2015 Feb 4. J Med Chem. 2015. PMID: 25581017 Free PMC article.

4

Successful applications of computer aided drug discovery: moving drugs from concept to the clinic.

Talele TT, Khedkar SA, Rigby AC. Talele TT, et al. Among authors: khedkar sa. Curr Top Med Chem. 2010;10(1):127-41. doi: 10.2174/156802610790232251. Curr Top Med Chem. 2010. PMID: 19929824 Review.

5

Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.

Thadhani R, Kisner T, Hagmann H, Bossung V, Noack S, Schaarschmidt W, Jank A, Kribs A, Cornely OA, Kreyssig C, Hemphill L, Rigby AC, Khedkar S, Lindner TH, Mallmann P, Stepan H, Karumanchi SA, Benzing T. Thadhani R, et al. Among authors: khedkar s. Circulation. 2011 Aug 23;124(8):940-50. doi: 10.1161/CIRCULATIONAHA.111.034793. Epub 2011 Aug 1. Circulation. 2011. PMID: 21810665 Clinical Trial.

6

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.

Gerald D, Adini I, Shechter S, Perruzzi C, Varnau J, Hopkins B, Kazerounian S, Kurschat P, Blachon S, Khedkar S, Bagchi M, Sherris D, Prendergast GC, Klagsbrun M, Stuhlmann H, Rigby AC, Nagy JA, Benjamin LE. Gerald D, et al. Nat Commun. 2013;4:2824. doi: 10.1038/ncomms3824. Nat Commun. 2013. PMID: 24280686 Free PMC article.

7

Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.

Patil SP, Maki S, Khedkar SA, Rigby AC, Chan C. Patil SP, et al. Among authors: khedkar sa. J Nat Prod. 2010 Jul 23;73(7):1196-202. doi: 10.1021/np900633j. J Nat Prod. 2010. PMID: 20553006 Free PMC article.

8

Resolution Agonist 15-epi-Lipoxin A₄ Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing.

Kain V, Liu F, Kozlovskaya V, Ingle KA, Bolisetty S, Agarwal A, Khedkar S, Prabhu SD, Kharlampieva E, Halade GV. Kain V, et al. Sci Rep. 2017 Aug 30;7(1):9999. doi: 10.1038/s41598-017-10441-8. Sci Rep. 2017. PMID: 28855632 Free PMC article.

9

Pharmacophore modeling in drug discovery and development: an overview.

Khedkar SA, Malde AK, Coutinho EC, Srivastava S. Khedkar SA, et al. Med Chem. 2007 Mar;3(2):187-97. doi: 10.2174/157340607780059521. Med Chem. 2007. PMID: 17348856 Review.

10

Current computational approaches in medicinal chemistry.

Khedkar SA. Khedkar SA. Curr Top Med Chem. 2010;10(1):1-2. doi: 10.2174/156802610790232323. Curr Top Med Chem. 2010. PMID: 20374194 No abstract available.

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