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Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin.
Saridakis E, Giastas P, Efthymiou G, Thoma V, Moulis JM, Kyritsis P, Mavridis IM. Saridakis E, et al. J Biol Inorg Chem. 2009 Jun;14(5):783-99. doi: 10.1007/s00775-009-0492-x. Epub 2009 Mar 17. J Biol Inorg Chem. 2009. PMID: 19290553
Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A site.
Katsoulis IA, Kythreoti G, Papakyriakou A, Koltsida K, Anastasopoulou P, Stathakis CI, Mavridis I, Cottin T, Saridakis E, Vourloumis D. Katsoulis IA, et al. Among authors: saridakis e. Chembiochem. 2011 May 16;12(8):1188-92. doi: 10.1002/cbic.201100076. Epub 2011 May 6. Chembiochem. 2011. PMID: 21557427 No abstract available.
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
Evnouchidou I, Birtley J, Seregin S, Papakyriakou A, Zervoudi E, Samiotaki M, Panayotou G, Giastas P, Petrakis O, Georgiadis D, Amalfitano A, Saridakis E, Mavridis IM, Stratikos E. Evnouchidou I, et al. Among authors: saridakis e. J Immunol. 2012 Sep 1;189(5):2383-92. doi: 10.4049/jimmunol.1200918. Epub 2012 Jul 25. J Immunol. 2012. PMID: 22837489 Free PMC article.
Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses.
Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, Aldhamen YA, Amalfitano A, Mavridis IM, James E, Georgiadis D, Stratikos E. Zervoudi E, et al. Among authors: saridakis e. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19890-5. doi: 10.1073/pnas.1309781110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248368 Free PMC article.
Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.
Mpakali A, Giastas P, Deprez-Poulain R, Papakyriakou A, Koumantou D, Gealageas R, Tsoukalidou S, Vourloumis D, Mavridis IM, Stratikos E, Saridakis E. Mpakali A, et al. Among authors: saridakis e. ACS Med Chem Lett. 2017 Feb 21;8(3):333-337. doi: 10.1021/acsmedchemlett.6b00505. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337326 Free PMC article.
56 results