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Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization.
Nakamoto N, Kaplan DE, Coleclough J, Li Y, Valiga ME, Kaminski M, Shaked A, Olthoff K, Gostick E, Price DA, Freeman GJ, Wherry EJ, Chang KM. Nakamoto N, et al. Among authors: wherry ej. Gastroenterology. 2008 Jun;134(7):1927-37, 1937.e1-2. doi: 10.1053/j.gastro.2008.02.033. Epub 2008 Feb 17. Gastroenterology. 2008. PMID: 18549878 Free PMC article.
T cell exhaustion.
Wherry EJ. Wherry EJ. Nat Immunol. 2011 Jun;12(6):492-9. doi: 10.1038/ni.2035. Nat Immunol. 2011. PMID: 21739672 Review.
Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults.
Herati RS, Reuter MA, Dolfi DV, Mansfield KD, Aung H, Badwan OZ, Kurupati RK, Kannan S, Ertl H, Schmader KE, Betts MR, Canaday DH, Wherry EJ. Herati RS, et al. Among authors: wherry ej. J Immunol. 2014 Oct 1;193(7):3528-37. doi: 10.4049/jimmunol.1302503. Epub 2014 Aug 29. J Immunol. 2014. PMID: 25172499 Free PMC article. Clinical Trial.
352 results