Kapur R - Search Results

1

Role of SHP2 in hematopoiesis and leukemogenesis.

Pandey R, Saxena M, Kapur R. Pandey R, et al. Among authors: kapur r. Curr Opin Hematol. 2017 Jul;24(4):307-313. doi: 10.1097/MOH.0000000000000345. Curr Opin Hematol. 2017. PMID: 28306669 Free PMC article. Review.

2

Requirement for p85alpha regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT.

Munugalavadla V, Sims EC, Chan RJ, Lenz SD, Kapur R. Munugalavadla V, et al. Among authors: kapur r. Exp Hematol. 2008 Mar;36(3):301-8. doi: 10.1016/j.exphem.2007.11.008. Epub 2008 Jan 7. Exp Hematol. 2008. PMID: 18179858 Free article.

3

Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors.

Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA. Benson EA, et al. Among authors: kapur r. Exp Hematol. 2010 Feb;38(2):71-81. doi: 10.1016/j.exphem.2009.11.006. Epub 2009 Nov 23. Exp Hematol. 2010. PMID: 19941935 Free PMC article.

4

Essential role for focal adhesion kinase in regulating stress hematopoiesis.

Vemula S, Ramdas B, Hanneman P, Martin J, Beggs HE, Kapur R. Vemula S, et al. Among authors: kapur r. Blood. 2010 Nov 18;116(20):4103-15. doi: 10.1182/blood-2010-01-262790. Epub 2010 Jul 27. Blood. 2010. PMID: 20664055 Free PMC article.

5

Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease.

Ma P, Mali RS, Martin H, Ramdas B, Sims E, Kapur R. Ma P, et al. Among authors: kapur r. Leukemia. 2012 Jul;26(7):1499-1506. doi: 10.1038/leu.2012.22. Epub 2012 Feb 2. Leukemia. 2012. PMID: 22297723 Free PMC article.

6

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.

Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, Bunting KD, Feng GS, Chan RJ, Zhang ZY, Kapur R. Mali RS, et al. Among authors: kapur r. Blood. 2012 Sep 27;120(13):2669-78. doi: 10.1182/blood-2011-08-375873. Epub 2012 Jul 17. Blood. 2012. PMID: 22806893 Free PMC article.

7

The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.

Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Zeng L, Richine B, Bowling JD, Fukuda S, Goenka S, Liu Z, Feng GS, Yu M, Sandusky GE, Boswell HS, Zhang ZY, Kapur R, Chan RJ. Nabinger SC, et al. Among authors: kapur r. Leukemia. 2013 Feb;27(2):398-408. doi: 10.1038/leu.2012.308. Epub 2012 Oct 22. Leukemia. 2013. PMID: 23103841 Free PMC article.

8

PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.

Goodwin CB, Li XJ, Mali RS, Chan G, Kang M, Liu Z, Vanhaesebroeck B, Neel BG, Loh ML, Lannutti BJ, Kapur R, Chan RJ. Goodwin CB, et al. Among authors: kapur r. Blood. 2014 May 1;123(18):2838-42. doi: 10.1182/blood-2013-10-535104. Epub 2014 Feb 19. Blood. 2014. PMID: 24553178 Free PMC article.

9

SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis.

Sharma N, Everingham S, Ramdas B, Kapur R, Craig AW. Sharma N, et al. Among authors: kapur r. J Immunol. 2014 May 15;192(10):4859-66. doi: 10.4049/jimmunol.1301155. Epub 2014 Apr 14. J Immunol. 2014. PMID: 24733849 Free PMC article.

10

PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal.

Kobayashi M, Bai Y, Dong Y, Yu H, Chen S, Gao R, Zhang L, Yoder MC, Kapur R, Zhang ZY, Liu Y. Kobayashi M, et al. Among authors: kapur r. Stem Cells. 2014 Jul;32(7):1956-67. doi: 10.1002/stem.1672. Stem Cells. 2014. PMID: 24753135 Free PMC article.

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