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Structure-based discovery of LpxC inhibitors.
Zhang J, Chan A, Lippa B, Cross JB, Liu C, Yin N, Romero JA, Lawrence J, Heney R, Herradura P, Goss J, Clark C, Abel C, Zhang Y, Poutsiaka KM, Epie F, Conrad M, Mahamoon A, Nguyen K, Chavan A, Clark E, Li TC, Cheng RK, Wood M, Andersen OA, Brooks M, Kwong J, Barker J, Parr IB, Gu Y, Ryan MD, Coleman S, Metcalf CA 3rd. Zhang J, et al. Among authors: liu c. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1670-1680. doi: 10.1016/j.bmcl.2017.03.006. Epub 2017 Mar 6. Bioorg Med Chem Lett. 2017. PMID: 28302397
Drug Development.
Raulin AC, Linares C, Alnobani A, Roy B, Crow A, Doss SV, Kuchenbecker LA, Dacquel MV, Karch CM, Martens YA, Liu CC, Bu G, Kanekiyo T. Raulin AC, et al. Among authors: liu cc. Alzheimers Dement. 2024 Dec;20 Suppl 6:e093237. doi: 10.1002/alz.093237. Alzheimers Dement. 2024. PMID: 39782478
Caveolin-1 mitigates the advancement of metabolic dysfunction-associated steatotic liver disease by reducing endoplasmic reticulum stress and pyroptosis through the restoration of cholesterol homeostasis.
Xu H, Li Y, Guo N, Wu S, Liu C, Gui Z, Xue W, Jiang X, Ye M, Geng Q, Feng X, Zhang C, Jin L, Hu C. Xu H, et al. Among authors: liu c. Int J Biol Sci. 2025 Jan 1;21(2):490-506. doi: 10.7150/ijbs.100794. eCollection 2025. Int J Biol Sci. 2025. PMID: 39781461 Free PMC article.
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