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Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain.
Jensen BA, Nielsen TS, Fritzen AM, Holm JB, Fjære E, Serup AK, Borkowski K, Risis S, Pærregaard SI, Søgaard I, Poupeau A, Poulsen M, Ma T, Sina C, Kiens B, Madsen L, Kristiansen K, Treebak JT. Jensen BA, et al. Among authors: sina c. Metabolism. 2016 Dec;65(12):1706-1719. doi: 10.1016/j.metabol.2016.09.002. Epub 2016 Sep 12. Metabolism. 2016. PMID: 27832859 Free article.
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice.
Banhos Danneskiold-Samsøe N, Sonne SB, Larsen JM, Hansen AN, Fjære E, Isidor MS, Petersen S, Henningsen J, Severi I, Sartini L, Schober Y, Wolf J, Nockher WA, Wolfrum C, Cinti S, Sina C, Hansen JB, Madsen L, Brix S, Kristiansen K. Banhos Danneskiold-Samsøe N, et al. Among authors: sina c. Sci Rep. 2019 Jun 20;9(1):8979. doi: 10.1038/s41598-019-45062-w. Sci Rep. 2019. PMID: 31222118 Free PMC article.
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism.
Jensen BAH, Holm JB, Larsen IS, von Burg N, Derer S, Sonne SB, Pærregaard SI, Damgaard MV, Indrelid SA, Rivollier A, Agrinier AL, Sulek K, Arnoldussen YJ, Fjære E, Marette A, Angell IL, Rudi K, Treebak JT, Madsen L, Åkesson CP, Agace W, Sina C, Kleiveland CR, Kristiansen K, Lea TE. Jensen BAH, et al. Among authors: sina c. Nat Commun. 2021 Feb 17;12(1):1093. doi: 10.1038/s41467-021-21408-9. Nat Commun. 2021. PMID: 33597537 Free PMC article.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: sina c. Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12. Nat Med. 2017. PMID: 28604704 Free PMC article.
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Stankiewicz TE, Sheridan R, Karns R, Cappelletti M, Lampe K, Mukherjee R, Sina C, Sallese A, Bridges JP, Hogan SP, Aronow BJ, Hoebe K, Divanovic S. Moreno-Fernandez ME, et al. Among authors: sina c. JCI Insight. 2018 Mar 22;3(6):e93626. doi: 10.1172/jci.insight.93626. JCI Insight. 2018. PMID: 29563328 Free PMC article.
139 results