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Page 1
Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.
Newton AC, Brognard J. Newton AC, et al. Among authors: brognard j. Trends Pharmacol Sci. 2017 May;38(5):438-447. doi: 10.1016/j.tips.2017.02.002. Epub 2017 Mar 8. Trends Pharmacol Sci. 2017. PMID: 28283201 Free PMC article. Review.
PHLiPPing the switch on Akt and protein kinase C signaling.
Brognard J, Newton AC. Brognard J, et al. Trends Endocrinol Metab. 2008 Aug;19(6):223-30. doi: 10.1016/j.tem.2008.04.001. Epub 2008 May 27. Trends Endocrinol Metab. 2008. PMID: 18511290 Free PMC article. Review.
Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output.
Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. Reyes G, et al. Among authors: brognard j. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E3957-65. doi: 10.1073/pnas.1404221111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201979 Free PMC article.
Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor.
Antal CE, Hudson AM, Kang E, Zanca C, Wirth C, Stephenson NL, Trotter EW, Gallegos LL, Miller CJ, Furnari FB, Hunter T, Brognard J, Newton AC. Antal CE, et al. Among authors: brognard j. Cell. 2015 Jan 29;160(3):489-502. doi: 10.1016/j.cell.2015.01.001. Epub 2015 Jan 22. Cell. 2015. PMID: 25619690 Free PMC article.
Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases.
Hudson AM, Stephenson NL, Li C, Trotter E, Fletcher AJ, Katona G, Bieniasz-Krzywiec P, Howell M, Wirth C, Furney S, Miller CJ, Brognard J. Hudson AM, et al. Among authors: brognard j. Sci Signal. 2018 Apr 17;11(526):eaan6776. doi: 10.1126/scisignal.aan6776. Sci Signal. 2018. PMID: 29666306 Free PMC article.
50 results