Beggs A - Search Results

1

BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis.

Horniblow RD, Bedford M, Hollingworth R, Evans S, Sutton E, Lal N, Beggs A, Iqbal TH, Tselepis C. Horniblow RD, et al. Among authors: beggs a. Cancer Sci. 2017 Jun;108(6):1135-1143. doi: 10.1111/cas.13234. Epub 2017 Jun 2. Cancer Sci. 2017. PMID: 28281325 Free PMC article.

2

An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy.

Lal N, Beggs AD, Willcox BE, Middleton GW. Lal N, et al. Oncoimmunology. 2015 Apr 2;4(3):e976052. doi: 10.4161/2162402X.2014.976052. eCollection 2015 Mar. Oncoimmunology. 2015. PMID: 25949894 Free PMC article.

3

Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium.

Pachnio A, Ciaurriz M, Begum J, Lal N, Zuo J, Beggs A, Moss P. Pachnio A, et al. Among authors: beggs a. PLoS Pathog. 2016 Sep 8;12(9):e1005832. doi: 10.1371/journal.ppat.1005832. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27606804 Free PMC article.

4

Mutation Frequencies in Patients With Early-Onset Colorectal Cancer.

Beggs AD. Beggs AD. JAMA Oncol. 2017 Nov 1;3(11):1585. doi: 10.1001/jamaoncol.2016.7089. JAMA Oncol. 2017. PMID: 28687834 No abstract available.

5

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q.

Lal N, Willcox CR, Beggs A, Taniere P, Shikotra A, Bradding P, Adams R, Fisher D, Middleton G, Tselepis C, Willcox BE. Lal N, et al. Among authors: beggs a. J Pathol Clin Res. 2017 Jul 14;3(3):155-170. doi: 10.1002/cjp2.70. eCollection 2017 Jul. J Pathol Clin Res. 2017. PMID: 28770100 Free PMC article.

6

KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.

Lal N, White BS, Goussous G, Pickles O, Mason MJ, Beggs AD, Taniere P, Willcox BE, Guinney J, Middleton GW. Lal N, et al. Clin Cancer Res. 2018 Jan 1;24(1):224-233. doi: 10.1158/1078-0432.CCR-17-1090. Epub 2017 Oct 23. Clin Cancer Res. 2018. PMID: 29061646 Free PMC article.

7

Discovery and Validation of Methylation Biomarkers for Ulcerative Colitis Associated Neoplasia.

Beggs AD, James J, Caldwell G, Prout T, Dilworth MP, Taniere P, Iqbal T, Morton DG, Matthews G. Beggs AD, et al. Inflamm Bowel Dis. 2018 Jun 8;24(7):1503-1509. doi: 10.1093/ibd/izy119. Inflamm Bowel Dis. 2018. PMID: 29762666 Free PMC article.

8

The evolutionary landscape of colorectal tumorigenesis.

Cross W, Kovac M, Mustonen V, Temko D, Davis H, Baker AM, Biswas S, Arnold R, Chegwidden L, Gatenbee C, Anderson AR, Koelzer VH, Martinez P, Jiang X, Domingo E, Woodcock DJ, Feng Y, Kovacova M, Maughan T; S:CORT Consortium; Jansen M, Rodriguez-Justo M, Ashraf S, Guy R, Cunningham C, East JE, Wedge DC, Wang LM, Palles C, Heinimann K, Sottoriva A, Leedham SJ, Graham TA, Tomlinson IPM. Cross W, et al. Nat Ecol Evol. 2018 Oct;2(10):1661-1672. doi: 10.1038/s41559-018-0642-z. Epub 2018 Aug 31. Nat Ecol Evol. 2018. PMID: 30177804 Free PMC article.

9

Validation of epigenetic markers to identify colitis associated cancer: Results of module 1 of the ENDCAP-C study.

Beggs AD, Mehta S, Deeks JJ, James JD, Caldwell GM, Dilworth MP, Stockton JD, Blakeway D, Pestinger V, Vince A, Taniere P, Iqbal T, Magill L, Matthews G, Morton DG; ENDCAP-C Module 1 Collaborative. Beggs AD, et al. EBioMedicine. 2019 Jan;39:265-271. doi: 10.1016/j.ebiom.2018.11.034. Epub 2018 Nov 22. EBioMedicine. 2019. PMID: 30473377 Free PMC article. Clinical Trial.

10

The Safety and Tolerability of a Potential Alginate-Based Iron Chelator; Results of A Healthy Participant Study.

Horniblow RD, Mistry P, Quraishi MN, Beggs AD, Van de Wiele T, Iqbal TH, Tselepis C. Horniblow RD, et al. Nutrients. 2019 Mar 21;11(3):674. doi: 10.3390/nu11030674. Nutrients. 2019. PMID: 30901846 Free PMC article.

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