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The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
Abraham M, Klein S, Bulvik B, Wald H, Weiss ID, Olam D, Weiss L, Beider K, Eizenberg O, Wald O, Galun E, Avigdor A, Benjamini O, Nagler A, Pereg Y, Tavor S, Peled A. Abraham M, et al. Among authors: klein s. Leukemia. 2017 Nov;31(11):2336-2346. doi: 10.1038/leu.2017.82. Epub 2017 Mar 10. Leukemia. 2017. PMID: 28280274
Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.
Barashi N, Weiss ID, Wald O, Wald H, Beider K, Abraham M, Klein S, Goldenberg D, Axelrod J, Pikarsky E, Abramovitch R, Zeira E, Galun E, Peled A. Barashi N, et al. Among authors: klein s. Hepatology. 2013 Sep;58(3):1021-30. doi: 10.1002/hep.26403. Epub 2013 Jul 12. Hepatology. 2013. PMID: 23526353
Single Dose of the CXCR4 Antagonist BL-8040 Induces Rapid Mobilization for the Collection of Human CD34+ Cells in Healthy Volunteers.
Abraham M, Pereg Y, Bulvik B, Klein S, Mishalian I, Wald H, Eizenberg O, Beider K, Nagler A, Golan R, Vainstein A, Aharon A, Galun E, Caraco Y, Or R, Peled A. Abraham M, et al. Among authors: klein s. Clin Cancer Res. 2017 Nov 15;23(22):6790-6801. doi: 10.1158/1078-0432.CCR-16-2919. Epub 2017 Aug 23. Clin Cancer Res. 2017. PMID: 28835380 Clinical Trial.
Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis.
Paldor M, Levkovitch-Siany O, Eidelshtein D, Adar R, Enk CD, Marmary Y, Elgavish S, Nevo Y, Benyamini H, Plaschkes I, Klein S, Mali A, Rose-John S, Peled A, Galun E, Axelrod JH. Paldor M, et al. Among authors: klein s. EMBO Mol Med. 2022 Aug 8;14(8):e15653. doi: 10.15252/emmm.202115653. Epub 2022 Jul 4. EMBO Mol Med. 2022. PMID: 35785521 Free PMC article.
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues.
Chai C, Rivkin M, Berkovits L, Simerzin A, Zorde-Khvalevsky E, Rosenberg N, Klein S, Yaish D, Durst R, Shpitzen S, Udi S, Tam J, Heeren J, Worthmann A, Schramm C, Kluwe J, Ravid R, Hornstein E, Giladi H, Galun E. Chai C, et al. Among authors: klein s. Gastroenterology. 2017 Nov;153(5):1404-1415. doi: 10.1053/j.gastro.2017.08.013. Epub 2017 Aug 9. Gastroenterology. 2017. PMID: 28802563
3,813 results