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Successful Transfer of Umbilical Cord Blood CD34+ Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients.
Dolstra H, Roeven MWH, Spanholtz J, Hangalapura BN, Tordoir M, Maas F, Leenders M, Bohme F, Kok N, Trilsbeek C, Paardekooper J, van der Waart AB, Westerweel PE, Snijders TJF, Cornelissen J, Bos G, Pruijt HFM, de Graaf AO, van der Reijden BA, Jansen JH, van der Meer A, Huls G, Cany J, Preijers F, Blijlevens NMA, Schaap NM. Dolstra H, et al. Among authors: spanholtz j. Clin Cancer Res. 2017 Aug 1;23(15):4107-4118. doi: 10.1158/1078-0432.CCR-16-2981. Epub 2017 Mar 9. Clin Cancer Res. 2017. PMID: 28280089 Clinical Trial.
Natural killer cell differentiation from hematopoietic stem cells: a comparative analysis of heparin- and stromal cell-supported methods.
Dezell SA, Ahn YO, Spanholtz J, Wang H, Weeres M, Jackson S, Cooley S, Dolstra H, Miller JS, Verneris MR. Dezell SA, et al. Among authors: spanholtz j. Biol Blood Marrow Transplant. 2012 Apr;18(4):536-45. doi: 10.1016/j.bbmt.2011.11.023. Epub 2011 Dec 7. Biol Blood Marrow Transplant. 2012. PMID: 22155502 Free PMC article.
Ex vivo generated natural killer cells acquire typical natural killer receptors and display a cytotoxic gene expression profile similar to peripheral blood natural killer cells.
Lehmann D, Spanholtz J, Osl M, Tordoir M, Lipnik K, Bilban M, Schlechta B, Dolstra H, Hofer E. Lehmann D, et al. Among authors: spanholtz j. Stem Cells Dev. 2012 Nov 1;21(16):2926-38. doi: 10.1089/scd.2011.0659. Epub 2012 Jul 17. Stem Cells Dev. 2012. PMID: 22571679 Free PMC article.
Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice.
Cany J, van der Waart AB, Tordoir M, Franssen GM, Hangalapura BN, de Vries J, Boerman O, Schaap N, van der Voort R, Spanholtz J, Dolstra H. Cany J, et al. Among authors: spanholtz j. PLoS One. 2013 Jun 5;8(6):e64384. doi: 10.1371/journal.pone.0064384. Print 2013. PLoS One. 2013. PMID: 23755121 Free PMC article.
The aryl hydrocarbon receptor antagonist StemRegenin 1 promotes human plasmacytoid and myeloid dendritic cell development from CD34+ hematopoietic progenitor cells.
Thordardottir S, Hangalapura BN, Hutten T, Cossu M, Spanholtz J, Schaap N, Radstake TR, van der Voort R, Dolstra H. Thordardottir S, et al. Among authors: spanholtz j. Stem Cells Dev. 2014 May 1;23(9):955-67. doi: 10.1089/scd.2013.0521. Epub 2014 Jan 24. Stem Cells Dev. 2014. PMID: 24325394 Clinical Trial.
35 results