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Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Lennartz F, Adams Y, Bengtsson A, Olsen RW, Turner L, Ndam NT, Ecklu-Mensah G, Moussiliou A, Ofori MF, Gamain B, Lusingu JP, Petersen JE, Wang CW, Nunes-Silva S, Jespersen JS, Lau CK, Theander TG, Lavstsen T, Hviid L, Higgins MK, Jensen AT. Lennartz F, et al. Among authors: wang cw. Cell Host Microbe. 2017 Mar 8;21(3):403-414. doi: 10.1016/j.chom.2017.02.009. Cell Host Microbe. 2017. PMID: 28279348 Free PMC article.
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children.
Lavstsen T, Turner L, Saguti F, Magistrado P, Rask TS, Jespersen JS, Wang CW, Berger SS, Baraka V, Marquard AM, Seguin-Orlando A, Willerslev E, Gilbert MT, Lusingu J, Theander TG. Lavstsen T, et al. Among authors: wang cw. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1791-800. doi: 10.1073/pnas.1120455109. Epub 2012 May 22. Proc Natl Acad Sci U S A. 2012. PMID: 22619319 Free PMC article.
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells.
Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA. Claessens A, et al. Among authors: wang cw. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1772-81. doi: 10.1073/pnas.1120461109. Epub 2012 May 22. Proc Natl Acad Sci U S A. 2012. PMID: 22619330 Free PMC article.
Severe malaria is associated with parasite binding to endothelial protein C receptor.
Turner L, Lavstsen T, Berger SS, Wang CW, Petersen JE, Avril M, Brazier AJ, Freeth J, Jespersen JS, Nielsen MA, Magistrado P, Lusingu J, Smith JD, Higgins MK, Theander TG. Turner L, et al. Among authors: wang cw. Nature. 2013 Jun 27;498(7455):502-5. doi: 10.1038/nature12216. Epub 2013 Jun 5. Nature. 2013. PMID: 23739325 Free PMC article.
1,183 results