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Page 1
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni S, Mancuso AB, Di Magno L, Sdruscia G, Manni S, Serrao SM, Rotili D, Spiombi E, Bufalieri F, Petroni M, Kusio-Kobialka M, De Smaele E, Ferretti E, Capalbo C, Mai A, Niewiadomski P, Screpanti I, Di Marcotullio L, Canettieri G. Coni S, et al. Among authors: canettieri g. Sci Rep. 2017 Mar 9;7:44079. doi: 10.1038/srep44079. Sci Rep. 2017. PMID: 28276480 Free PMC article.
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. De Smaele E, et al. Among authors: canettieri g. Neoplasia. 2008 Jan;10(1):89-98. doi: 10.1593/neo.07891. Neoplasia. 2008. PMID: 18231642 Free PMC article.
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Canettieri G, Coni S, Della Guardia M, Nocerino V, Antonucci L, Di Magno L, Screaton R, Screpanti I, Giannini G, Gulino A. Canettieri G, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1445-50. doi: 10.1073/pnas.0808749106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164581 Free PMC article.
TORCs/CRTCs: more than mere coincidence.
Canettieri G, Coni S, Antonucci L, Di Magno L, Gulino A. Canettieri G, et al. Cell Cycle. 2009 Apr 1;8(7):963-4. Epub 2009 Apr 9. Cell Cycle. 2009. PMID: 19287208 No abstract available.
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Canettieri G, et al. Nat Cell Biol. 2010 Feb;12(2):132-42. doi: 10.1038/ncb2013. Epub 2010 Jan 17. Nat Cell Biol. 2010. PMID: 20081843
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
Po A, Ferretti E, Miele E, De Smaele E, Paganelli A, Canettieri G, Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C, Screpanti I, Gulino A. Po A, et al. Among authors: canettieri g. EMBO J. 2010 Aug 4;29(15):2646-58. doi: 10.1038/emboj.2010.131. Epub 2010 Jun 25. EMBO J. 2010. PMID: 20581804 Free PMC article.
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. De Smaele E, et al. Among authors: canettieri g. Neoplasia. 2011 Apr;13(4):374-85. doi: 10.1593/neo.101630. Neoplasia. 2011. PMID: 21472142 Free PMC article.
94 results