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Page 1
Identification of novel TACE inhibitors compatible with topical application.
Ouvry G, Berton Y, Bhurruth-Alcor Y, Bonnary L, Bouix-Peter C, Bouquet K, Bourotte M, Chambon S, Comino C, Deprez B, Duvert D, Duvert G, Hacini-Rachinel F, Harris CS, Luzy AP, Mathieu A, Millois C, Pascau J, Pinto A, Polge G, Reitz A, Reversé K, Rosignoli C, Taquet N, Hennequin LF. Ouvry G, et al. Among authors: chambon s. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1848-1853. doi: 10.1016/j.bmcl.2017.02.035. Epub 2017 Feb 20. Bioorg Med Chem Lett. 2017. PMID: 28274635
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne.
Fournier JF, Clary L, Chambon S, Dumais L, Harris CS, Millois C, Pierre R, Talano S, Thoreau É, Aubert J, Aurelly M, Bouix-Peter C, Brethon A, Chantalat L, Christin O, Comino C, El-Bazbouz G, Ghilini AL, Isabet T, Lardy C, Luzy AP, Mathieu C, Mebrouk K, Orfila D, Pascau J, Reverse K, Roche D, Rodeschini V, Hennequin LF. Fournier JF, et al. Among authors: chambon s. J Med Chem. 2018 May 10;61(9):4030-4051. doi: 10.1021/acs.jmedchem.8b00067. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29648825
Structure-based design of Trifarotene (CD5789), a potent and selective RARγ agonist for the treatment of acne.
Thoreau E, Arlabosse JM, Bouix-Peter C, Chambon S, Chantalat L, Daver S, Dumais L, Duvert G, Feret A, Ouvry G, Pascau J, Raffin C, Rodeville N, Soulet C, Tabet S, Talano S, Portal T. Thoreau E, et al. Among authors: chambon s. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1736-1741. doi: 10.1016/j.bmcl.2018.04.036. Epub 2018 Apr 15. Bioorg Med Chem Lett. 2018. PMID: 29706423
Novel library synthesis of 3,4-disubstituted pyridin-2(1H)-ones via cleavage of pyridine-2-oxy-7-azabenzotriazole ethers under ionic hydrogenation conditions at room temperature.
Pierre R, Brethon A, Jacques SA, Blond A, Chambon S, Talano S, Raffin C, Musicki B, Bouix-Peter C, Tomas L, Ouvry G, Morgentin R, Hennequin LF, Harris CS. Pierre R, et al. Among authors: chambon s. Beilstein J Org Chem. 2021 Jan 18;17:156-165. doi: 10.3762/bjoc.17.16. eCollection 2021. Beilstein J Org Chem. 2021. PMID: 33564326 Free PMC article.
Identification of unknown impurities J, RRT 2.2, 2.4, 2.6 and 3.4 in tetralysal® capsules.
Billié S, Reversé K, Arlabosse JM, Bertin D, Boulier A, Cachot T, Chambon S, Charras K, Cren C, Furnes B, Gerfaud T, Joly-Battaglini M, Longoni D, Mouis G, Pierre R, Raynard H, Texier T, Trognon C, Zanelli U, Boiteau JG, Harris CS. Billié S, et al. Among authors: chambon s. Eur J Pharm Sci. 2023 Sep 1;188:106519. doi: 10.1016/j.ejps.2023.106519. Epub 2023 Jul 19. Eur J Pharm Sci. 2023. PMID: 37478583 Free article.
Completion of the impurity profile of lymecycline: Formal identification of impurities E and F.
Billié S, Reversé K, Chambon S, Cachot T, Pierre R, Gerfaud T, Longoni D, Gennari M, Raynard H, Talbot E, Charras K, Bertin D, Joly-Battaglini M, Pedrassi G, Boiteau JG, Cren C, Harris CS. Billié S, et al. Among authors: chambon s. J Pharm Biomed Anal. 2022 Oct 25;220:114993. doi: 10.1016/j.jpba.2022.114993. Epub 2022 Aug 11. J Pharm Biomed Anal. 2022. PMID: 36007309
32 results