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Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption.
Siddiqui S, Lustig A, Carter A, Sankar M, Daimon CM, Premont RT, Etienne H, van Gastel J, Azmi A, Janssens J, Becker KG, Zhang Y, Wood W, Lehrmann E, Martin JG, Martin B, Taub DD, Maudsley S. Siddiqui S, et al. Among authors: premont rt. Aging (Albany NY). 2017 Mar 4;9(3):706-740. doi: 10.18632/aging.101185. Aging (Albany NY). 2017. PMID: 28260693 Free PMC article.
Nuclear GIT2 is an ATM substrate and promotes DNA repair.
Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S. Lu D, et al. Among authors: premont rt. Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20. Mol Cell Biol. 2015. PMID: 25605334 Free PMC article.
GIT2-A keystone in ageing and age-related disease.
van Gastel J, Boddaert J, Jushaj A, Premont RT, Luttrell LM, Janssens J, Martin B, Maudsley S. van Gastel J, et al. Among authors: premont rt. Ageing Res Rev. 2018 May;43:46-63. doi: 10.1016/j.arr.2018.02.002. Epub 2018 Feb 13. Ageing Res Rev. 2018. PMID: 29452267 Review.
GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.
Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. Martin B, et al. Among authors: premont rt. Front Endocrinol (Lausanne). 2016 Jan 18;6:191. doi: 10.3389/fendo.2015.00191. eCollection 2015. Front Endocrinol (Lausanne). 2016. PMID: 26834700 Free PMC article.
Correction for Lu et al., "Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair".
Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S. Lu D, et al. Among authors: premont rt. Mol Cell Biol. 2017 Aug 11;37(17):e00310-17. doi: 10.1128/MCB.00310-17. Print 2017 Sep 1. Mol Cell Biol. 2017. PMID: 28801458 Free PMC article. No abstract available.
Anxiety-like behaviors in mice lacking GIT2.
Schmalzigaug R, Rodriguiz RM, Phillips LE, Davidson CE, Wetsel WC, Premont RT. Schmalzigaug R, et al. Among authors: premont rt. Neurosci Lett. 2009 Feb 20;451(2):156-61. doi: 10.1016/j.neulet.2008.12.034. Epub 2008 Dec 24. Neurosci Lett. 2009. PMID: 19114090 Free PMC article.
168 results