Nguyen HD - Search Results

1

ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.

Yazinski SA, Comaills V, Buisson R, Genois MM, Nguyen HD, Ho CK, Todorova Kwan T, Morris R, Lauffer S, Nussenzweig A, Ramaswamy S, Benes CH, Haber DA, Maheswaran S, Birrer MJ, Zou L. Yazinski SA, et al. Among authors: nguyen hd. Genes Dev. 2017 Feb 1;31(3):318-332. doi: 10.1101/gad.290957.116. Epub 2017 Feb 27. Genes Dev. 2017. PMID: 28242626 Free PMC article.

2

Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.

Shiotani B, Nguyen HD, Håkansson P, Maréchal A, Tse A, Tahara H, Zou L. Shiotani B, et al. Among authors: nguyen hd. Cell Rep. 2013 May 30;3(5):1651-62. doi: 10.1016/j.celrep.2013.04.018. Epub 2013 May 16. Cell Rep. 2013. PMID: 23684611 Free PMC article.

3

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

Maréchal A, Li JM, Ji XY, Wu CS, Yazinski SA, Nguyen HD, Liu S, Jiménez AE, Jin J, Zou L. Maréchal A, et al. Among authors: nguyen hd. Mol Cell. 2014 Jan 23;53(2):235-246. doi: 10.1016/j.molcel.2013.11.002. Epub 2013 Dec 12. Mol Cell. 2014. PMID: 24332808 Free PMC article.

4

SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway.

Wu CS, Ouyang J, Mori E, Nguyen HD, Maréchal A, Hallet A, Chen DJ, Zou L. Wu CS, et al. Among authors: nguyen hd. Genes Dev. 2014 Jul 1;28(13):1472-84. doi: 10.1101/gad.238535.114. Genes Dev. 2014. PMID: 24990965 Free PMC article.

5

Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.

Ouyang J, Garner E, Hallet A, Nguyen HD, Rickman KA, Gill G, Smogorzewska A, Zou L. Ouyang J, et al. Among authors: nguyen hd. Mol Cell. 2015 Jan 8;57(1):108-22. doi: 10.1016/j.molcel.2014.11.015. Epub 2014 Dec 18. Mol Cell. 2015. PMID: 25533185 Free PMC article.

6

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1.

Nguyen HD, Yadav T, Giri S, Saez B, Graubert TA, Zou L. Nguyen HD, et al. Mol Cell. 2017 Mar 2;65(5):832-847.e4. doi: 10.1016/j.molcel.2017.01.029. Mol Cell. 2017. PMID: 28257700 Free PMC article.

7

A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation.

Kabeche L, Nguyen HD, Buisson R, Zou L. Kabeche L, et al. Among authors: nguyen hd. Science. 2018 Jan 5;359(6371):108-114. doi: 10.1126/science.aan6490. Epub 2017 Nov 23. Science. 2018. PMID: 29170278 Free PMC article.

8

Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes.

Nguyen HD, Leong WY, Li W, Reddy PNG, Sullivan JD, Walter MJ, Zou L, Graubert TA. Nguyen HD, et al. Cancer Res. 2018 Sep 15;78(18):5363-5374. doi: 10.1158/0008-5472.CAN-17-3970. Epub 2018 Jul 27. Cancer Res. 2018. PMID: 30054334 Free PMC article.

9

Getting a Genomic View of DNA Replication Stress.

Zou L, Nguyen HD. Zou L, et al. Among authors: nguyen hd. Mol Cell. 2018 Oct 18;72(2):201-203. doi: 10.1016/j.molcel.2018.10.001. Mol Cell. 2018. PMID: 30340018 Free article.

10

Targeting R-loop-associated ATR response in myelodysplastic syndrome.

Nguyen HD, Zou L, Graubert TA. Nguyen HD, et al. Oncotarget. 2019 Apr 5;10(27):2581-2582. doi: 10.18632/oncotarget.26851. eCollection 2019 Apr 5. Oncotarget. 2019. PMID: 31080550 Free PMC article. No abstract available.

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